Short Term Control of Blood Pressure Flashcards

1
Q

MAP is

A

The driving force pushing blood through the circulation

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2
Q

Result if MAP is too low

A

Fainting (syncope)

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3
Q

Result if MAP is too high

A

Hypertension

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4
Q

Receptors of blood pressure involved in arterial baroreceptor reflex

A

Aortic arch baroreceptor and carotid sinus baroreceptors

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5
Q

Baroreceptors indirectly measure pressure by measuring

A

Stretch

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6
Q

As MAP increases, baroreceptor firing

A

Increases

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7
Q

Two sensory nerves of arterial baroreflex

A

Vagus nerve

Glossopharyngeal nerve

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8
Q

Two motor nerves of arterial baroreflex

A

Parasympathetic vagus nerve

Sympathetic nerves

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9
Q

Medullary cardiovascular centres

A

Several different groups of neurons in medulla communicating that take impulses of MAP and decide what to do about it

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10
Q

Outcomes of the arterial baroreflex via parasympathetic nerves

A

Decreases blood pressure via sinoatrial node depolarising less

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11
Q

Outcomes of the arterial baroreflex via sympathetic nerves (not including smooth muscle)

A

Increase blood pressure via sinoatrial node depolarising more, adrenal medulla releasing adrenaline, myocardium releasing more calcium ions from sarcoplasmic reticulum increasing contractility and so SV

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12
Q

Outcomes of the arterial baroreflex via smooth muscle (controlled by sympathetic nerves)

A

Vasoconstriction increasing stroke volume and arteriolar constriction increasing TPR

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13
Q

Other inputs to the medullary cardiovascular centres

A
Cardiopulmonary baroreceptors
Central chemoreceptors
Chemoreceptors in muscle
Joint receptor
Higher centres
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14
Q

Cardiopulmonary baroreceptors

A

In the walls of the vessels in heart and lungs which are the low pressure parts of circulation, detect increase in blood pressure

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15
Q

Central chemoreceptors

A

Detect carbon dioxide levels, more co2 = more o2 and so increase in blood pressure

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16
Q

Chemoreceptors in muscle

A

Respond to high potassium ion concentration or acidity, signify high metabolic activity, need more blood so increase blood pressure

17
Q

Joint receptors

A

Greater work in joints requires more blood and so increases blood pressure

18
Q

Higher centres

A

Feed forward effect in the cortex effected by emotions

19
Q

Main sensors in the regulation of blood pressure in the long term

A

Cardiopulmonary baroreceptors

20
Q

Long term regulation of blood pressure act on

A

Vessels and kidneys

21
Q

Result of standing up

A

Increased hydrostatic pressure causes pooling of blood in veins and venules of legs and feet

22
Q

Effect of standing on blood pressure

A

Decrease in VR, EDV, preload, SV, CO, MAP and baroreceptor firing

23
Q

Reflex response to blood pressure changes due to standing

A

Decrease in vagal tone so no longer slowing down the heart increasing HR and CO
Increase in sympathetic tone increasing HR, contractility, venoconstriction and arteriolar constriction

24
Q

The Valsalva manoeuvre

A

Forced expiration against a closed glottis

25
Q

Result of Valsalva manoeuvre

A

Increases thoracic pressure which is transmitted through to aorta

26
Q

Effect of Valsalva manoeuvre on blood pressure

A

Reverses pressure gradient, decrease in VR, EDV, SV, CO, MAP

27
Q

Reflex response to blood pressure changes due to Valsalva manoeuvre

A

Decrease in MAP is detected by baroreceptors which initiates reflex and increases CO and TPR, the decrease in thoracic pressure is transmitted through to aorta and VR so SV is restored but reflex effects not worn off, then return to normal

28
Q

Regulation of blood pressure in the long term revolves around

A

Blood volume