Aortic Aneurysms and Carotid Artery Disease Flashcards
Aneurysm disease
Dilation of all layers of the aorta leading to an increase in diameter of >50%
Causes of aneurysm disease
Degenerative disease
Connective tissue disease
Infection (mycotic aneurysm)
Risk factors for degenerative abdominal aortic aneurysms
Male Age Smoking Hypertension Family history
Prevalence of aortic aneurysm disease in the UK
3%
Symptoms of abdominal aortic aneurysm
Asymptomatic
Abdominal aortic aneurysm can only be detected by
Screening
Type of screening used for abdominal aortic aneurysm
Ultrasound scan
A good screening is one which
Minimises false positives and negatives, maximises true positives and negatives
Presentation of impending rupture of abdominal aortic aneurysm
Increasing back pain
Tender abdominal aortic aneurysm
Presentation of ruptured abdominal aortic aneurysm
Abdominal and back pain
Painful pulsatile mass
Haemodynamic instability
Hypoperfusion
Usual presentations of abdominal aortic aneurysms in scan
Distal embolisation Aortocaval fistula Aortoenteric fistula Ureteric occlusion Duodenal obstruction
Treatment options for abdominal aortic aneurysm
Conservative
Endovascular repair
Open repair
Endovascular repair
Insertion of stent graft into aneurysm
Open repair general complications
Wound infection or separation
Bleeding
Pain
Scar
Open repair technical complications
Damage to bowel, ureters, veins, nerves Incisional hernia Graft infection Distal emboli Renal failure Colonic ischaemia
Open repair and endovascular repair patient factor complications
Deep vein thrombosis/pulmonary embolism
MI
Stroke
Death
Endovascular repair general complications
Wound infection Bleeding/haematoma Pain Scar Radiation Contrast - kidney injury
Endovascular repair technical complications
Endoleak
Femoral artery dissection/pseudo-aneurysm
Rupture
Distal emboli/ischaemia/colonic ischaemia
Damage to femoral vein/nerve
Emergency open repair of abdominal aortic aneurysm
Laparotomy xiphisternum to public symphysis to occlude aortic proximally
Surveillance of abdominal aortic aneurysm until it reaches a diameter of
5.5cm
Atherosclerosis of carotid arteries can result in
Ischaemic attacks and stroke
Transient ischaemic attack
Focal CNS disturbance caused by vascular events leading to cerebral ischaemia, lasts less than 24 hours
Stroke
Clinical syndrome consisting of rapidly developing clinical signs of focal or global disturbance of cerebral function due to vascular event, lasts more than 24 hours
Causes of stroke/TIA
Cerebral infarction
Primary intracerebal haemorrhage
Subarachnoid haemorrhage
Causes of cerebral infarction
Atrial fibrillation Carotid atherosclerosis - rupture/thrombus Endocarditis MI Carotid artery trauma/dissection Drug abuse Haematological disorder
Risk factors for carotid artery atherosclerosis
Smoking Dibetes Family history Male Hypertension Hyperlipidaemia/hypercholesterolaemia Obesity Age
Imaging for carotid artery atherosclerosis
CT and carotid ultrasound
Effect of decrease in vessel radius on velocity
Increases
Degree of stenosis can be measured via
Measuring velocity
Best medical therapy for carotid artery atherosclerosis
Smoking cessation Control of hypertension Anti-platelet Statin Diabetic control
Statin
Drug that lowers cholesterol levels in the blood
The brain is still perfused despite carotid artery atherosclerosis due to
Circle of Willis
Carotid endarterectomy
Removal of plaque from artery
Complications of carotid endarterectomy
Wound infection Bleeding Scar Anaesthetic risks Nerve damage - vagus and hypoglossal Preoperative stroke
Management of carotid artery atherosclerosis
Best medical therapy
Carotid endarterectomy
Stenting
Timing of management
Longer carotid is left alone the more stable the plaque becomes
The NNT to prevent one stroke for men and women
Men - 9
Women - 36
Most risky period for further event is within
The first 2 weeks
Prophylactic
Doesn’t reverse effects of stroke, just prevents further events
Surgery is described as being
Prophylactic
Carotid surgery should be offered to
Symptomatic patients with >70% stenosis
Surgery in men considered if stenosis percentage is between
50-69%
Surgery in asymptomatic patients considered if stenosis percentage is >
70%