Shock Syndromes Flashcards
What are the causes of hypovolemic shock?
- loss of intravascular fluids
- surgery
- trauma
- hemorrhage
- severe dehydration
What are the causes of distributive shock?
- loss of vascular tone
- sepsis
- spinal cord injury
- anaphylaxis
What are the causes of cardiogenic shock?
- loss of pump function
- acute MI\
- valve abnormality
- arrhythmias
- HF
What are the causes of obstructive shock?
- extra cardiac obstruction to blood flow
- tension pneumothorax
- cardiac tamponade
- PE
What does B1 activation on the heart result in?
- positive inotrope- increase force of contraction
- chronotrope- increase HR
What does B2 activation on the lungs and vasculature result in?
- bronchodilation
- vasodilation- decrease afterload/ SVR
What does a1 activation on the vasculature result in?
vasoconstriction- increased afterload/ SVR
What does V1 activation on the vasculature result in?
vasoconstriction- increased afterload/ SVR
What does angiotensin 1 activation on the arterioles result in?
vasoconstriction- increased afterload/ SVR
What activity does low dose (<2mcg/kg) DA have as a vasopressor?
mostly B1
What activity does moderate dose (2-10 mcg/kg) DA have as a vasopressor?
mostly B1;
some a1
What activity does high dose (>10mcg/kg) DA have as a vasopressor?
B1 and a1
What kind of vasopressor activity does NE have?
mostly a1;
some B1
What vasopressor is preferred in sepsis?
NE
What kind of vasopressor activity does phenylephrine have?
strong a1
