Acid/Base Flashcards
What is a normal arterial blood gas pH?
7.35-7.45
What is a normal arterial blood gas PaCO2?
35-45 mmHg
What is a normal arterial blood gas HCO3-?
24-30 mEq/L
What is the cause of respiratory acidosis or alkalosis?
disturbance in CO2
What is the cause of metabolic acidosis or alkalosis?
disturbance of HCO3- (kidneys)
How is respiratory acidosis treated?
- reversal agents
- diuretics
- steroids
- bronchodilators
- ventilator management
How is respiratory alkalosis treated?
- ventilator management
- anxiety management
How is metabolic alkalosis treated?
- Cl solutions
- dilute hydrochloric acid
- carbonic anhydrase inhibitor (Acetazolamide)
How is Acetazolamide dosed for metabolic alkalosis?
500mg IV bolus/ Q12-24H
How does Acetazolamide treat metabolic alkalosis?
excretion of bicarb lowers pH
How is metabolic acidosis treated?
- Sodium bicarbonate 50 mEq (1amp) IV bolus
- Sodium bicarbonate 150 mEq (3amp) in 1L sterile water or D5W continuous infusion
What role does THAM have in metabolic acidosis treatment? How is it dosed?
- salvage therapy
- 500mL IV
What is the purpose of calculating the anion gap?
helps determine the cause of METABOLIC ACIDOSIS ONLY
How is anion gap calculated?
Na-Cl-HCO3
What is an elevated anion gap?
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