Shock, C26 P164-170 Flashcards
What is the definition of shock?
P164
Inadequate tissue perfusion
What are the different types (5)?
P164
Hypovolemic Septic Cardiogenic Neurogenic Anaphylactic
What are the signs of shock?
P165
Pale, diaphoretic, cool skin Hypotension, tachycardia, tachypnea ↓ mental status and pulse pressure Poor capillary refill Poor urine output
What are the best indicators of tissue perfusion?
P165
Urine output, mental status
What lab tests help assess tissue perfusion?
P165
Lactic acid (elevated with inadequate tissue perfusion), base deficit, pH from ABG (acidosis associated with inadequate tissue perfusion)
HYPOVOLEMIC SHOCK
What is the definition?
P165
Decreased intravascular volume
HYPOVOLEMIC SHOCK
What are the common causes?
P165
Hemorrhage Burns Bowel obstruction Crush injury Pancreatitis
HYPOVOLEMIC SHOCK
What are the signs?
P165
Early—Orthostatic hypotension, mild
tachycardia, anxiety, diaphoresis,
vasoconstriction (decreased pulse pressure
with increased diastolic pressure)
Late—Changed mental status, decreased BP,
marked tachycardia
HYPOVOLEMIC SHOCK
What are the signs/ symptoms with:
Class I hemorrhage (<15% or 750 cc blood loss)?P165
Mild anxiety, normal vital signs
HYPOVOLEMIC SHOCK
What are the signs/ symptoms with:
Class II hemorrhage (15%–30% or 750–1500 cc blood loss)?
P165
Normal systolic BP with decreased pulse
pressure, tachycardia, tachypnea, anxiety
HYPOVOLEMIC SHOCK
What are the signs/ symptoms with:
Class III hemorrhage (30%–40% or 1500–2000 cc blood loss)?
P165
Tachycardia (heart rate >120), tachypnea
(respiratory rate >30), decreased
systolic BP, decreased pulse pressure,
confusion
HYPOVOLEMIC SHOCK What are the signs/ symptoms with: Class IV hemorrhage ( >40% or >2000 cc blood loss)? P166
Decreased systolic BP, tachycardia (heart
rate >140), tachypnea (respiratory rate >35), decreased pulse pressure, confused
and lethargic, no urine output
HYPOVOLEMIC SHOCK
What is the treatment?
P166
- Stop the bleeding
- Volume: IVF (isotonic LR) then blood
products as needed
HYPOVOLEMIC SHOCK
How is the effectiveness of treatment evaluated:
Bedside indicator?
P166
Urine output, BP, heart rate, mental status, extremity warmth, capillary refill, body temperature
HYPOVOLEMIC SHOCK
How is the effectiveness of treatment evaluated:
Labs?
P166
pH, base deficit, and lactate level
HYPOVOLEMIC SHOCK
What usually causes failure of resuscitation?
P166
Persistent massive hemorrhage, requiring
emergent surgical procedure
HYPOVOLEMIC SHOCK
Why does decreased pulse pressure occur with early hypovolemic shock?
P166
Pulse pressure (systolic–diastolic BP) decreases because of vasoconstriction, resulting in an elevated diastolic BP
HYPOVOLEMIC SHOCK
What is the most common vital sign change associated with early hypovolemic shock?
P166
Tachycardia
HYPOVOLEMIC SHOCK
What type of patient does not mount a normal
tachycardiac response to hypovolemic shock?
P166
Patients on ℬ-blockers, spinal shock
(loss of sympathetic tone), endurance athletes
HYPOVOLEMIC SHOCK
Should vasopressors be used to treat hypovolemic shock?
P166
No
HYPOVOLEMIC SHOCK
Should patients with hypovolemic shock be put
into the Trendelenburg position?
P166
No
SEPTIC SHOCK
What is the definition?
P167
Documented infection and hypotension
SEPTIC SHOCK
What is the specific etiology?
P167
Most common—gram-negative septicemia
Less common—gram-positive septicemia,
fungus
SEPTIC SHOCK
What factors increase the susceptibility to septic
shock?
P167
Any mechanism that increases susceptibility to infection (e.g., trauma, immunosuppression, corticosteroids, hematologic disease, diabetes)
SEPTIC SHOCK
What complications are major risks in septic shock?
P167
Multiple organ failure, DIC, death
SEPTIC SHOCK
What are the signs/symptoms?
P167
Initial—vasodilation, resulting in warm skin and
full pulses; normal urine output
Delayed—vasoconstriction and poor urine
output; mental status changes; hypotension
SEPTIC SHOCK
What percentage of blood cultures is positive in
patients with bacterial septic shock?
P167
Only about 50%!
SEPTIC SHOCK
What are the associated findings?
P167
Fever, hyperventilation, tachycardia
SEPTIC SHOCK
What are the associated lab findings?
P167
Early—hyperglycemia/glycosuria, respiratory
alkalosis, hemoconcentration, leukopenia
Late—leukocytosis, acidosis, elevated lactic acid
(Note: Identifying organism is important
to direct treatment/antibiotics)
SEPTIC SHOCK
What is the treatment?
P167
- Volume (IVF)
- Antibiotics (empiric, then by cultures)
- Drainage of infection
- Pressors PRN
- Zygris® PRN
SEPTIC SHOCK
What is Zygris®?
P168
Activated protein C, shown to decrease mortality in septic shock and multiple organ failure
CARDIOGENIC SHOCK
What is the definition?
P168
Cardiac insufficiency; left ventricular failure (usually), resulting in inadequate tissue perfusion
CARDIOGENIC SHOCK
What are the causes?
P168
MI, papillary muscle dysfunction, massive cardiac contusion, cardiac tamponade,
tension pneumothorax, cardiac valve failure
CARDIOGENIC SHOCK
What are the signs/symptoms on exam?
P168
Dyspnea Rales Pulsus alternans (increased pulse with greater filling following a weak pulse) Loud pulmonic component of S(2) Gallop rhythm
CARDIOGENIC SHOCK
What are the associated vital signs/parameters?
P168
Hypotension, decreased cardiac output,
elevated CVP/wedge pressure, decreased
urine output (low renal blood flow), tachycardia (possibly)
CARDIOGENIC SHOCK
What are the signs on CXR?
P168
Pulmonary edema
CARDIOGENIC SHOCK
What is the treatment?
P168
Based on diagnosis/mechanism:
1. CHF: diuretics and afterload reduction
(e.g., ACE inhibitors), with or without pressors
2. Left ventricular failure (MI):
pressors, afterload reduction
CARDIOGENIC SHOCK
What are the last resort support mechanisms?
P168
Intra-aortic balloon pump (IABP),
ventricular assist device (VAD)
NEUROGENIC SHOCK
What is the definition?
P168
Inadequate tissue perfusion from loss of
sympathetic vasoconstrictive tone
NEUROGENIC SHOCK
What are the common causes?
P168
Spinal cord injury:
- Complete transection of spinal cord
- Partial cord injury with spinal shock
- Spinal anesthesia
NEUROGENIC SHOCK
What are the signs/symptoms?
P169
Hypotension and bradycardia, neurologic deficit
NEUROGENIC SHOCK
Why are heart rate and BP decreased?
P169
Loss of sympathetic tone
(but hypovolemia [e.g., hemoperitoneum]
must be ruled out)
NEUROGENIC SHOCK
What are the associated findings?
P169
Neurologic deficits suggesting cord injury
NEUROGENIC SHOCK
What MUST be ruled out in any patient where spinal shock is suspected?
P169
Hemorrhagic shock!
NEUROGENIC SHOCK
What is the treatment?
P169
IV fluids (vasopressors reserved for hypotension refractory to fluid resuscitation)
NEUROGENIC SHOCK
What percentage of patients with hypotension and spinal neurologic deficits have hypotension of purely neurogenic origin?
P169
About 67% (two thirds) of patients
NEUROGENIC SHOCK
What is spinal shock?
P169
Complete flaccid paralysis immediately
following spinal cord injury; may or may
not be associated with circulatory shock
NEUROGENIC SHOCK
What is the lowest reflex available to the examiner?
P169
Bulbocavernous reflex: checking for
contraction of the anal sphincter upon
compression of the glans penis or clitoris
NEUROGENIC SHOCK
What is the lowest level voluntary muscle?
P169
External anal sphincter
NEUROGENIC SHOCK
What are the classic findings associated with spinal cord shock?
P169
Hypotension
Bradycardia or lack of compensatory
tachycardia
MISCELLANEOUS
What is the acronym for treatment options for
anaphylactic shock?
P169
“BASE”: Benadryl Aminophylline Steroids Epinephrine