Shit gotta know - exercise + repro Flashcards
name 3 physiological changes that can occur with exercise training
increased GLUT 4 expression, increased muscle blood flow, increased capillary density/recruitment
3 mitochondrial adaptations to exercise
increased density and oxidative enzymes, reduced CHO use and lactate production, increased fat oxidation
impact of exercise on warfarin?
decreased INR. Warfarin less effective so more likely to clot
define sarcopenia and what is needed for diagnosis?
age-associated loss of skeletal muscle mass and function.Diagnosis = low muscle mass + low muscle strength or low physical performance
what happens in regard to the muscle fibre types in sarcopenia and what age does this begin.
from 50 fast twitch fibres start to become replaced by slow twitch.
name 4 exercise types that can aid in healthy aging
strength training, aerobic, flexibility, balance
which type of hormones decline with age? list 3 and how they impact muscle wasting
anabolic - GH, IGF-1 and testosterone. Low levels compromise the efficiency of muscle regeneration as a consequence of damage from daily wear and tear
describe genetics and pathology of DMD
X lnked recessive causes lack of the protein dystrophin. Lack of this protein affects muscles ability to regenerate after contraction damage.
differences between DMD & BMD (clinical and molecular)
BMD less severe with later onset (adolescence or adulthood) and slower progression. Survival well into mid-late adulthood. In BMD there is abnormal, smaller amounts of dystrophin c.f. absolutely none in DMD
non-genomic way glucocorticoids inhibit inflammation?
inhibit Arachidonic acid release
4 adverse effects of NSAIDS
gastro-intestinal, increase bleeding time, renal & pulmonary
how may NSAIDs act on renal and pulmonary systems respectively
compromise renal blood flow & bronchoconstrict
name the 5 STIs covered in the lecture?
N. Gonorrhea.Clamydia Trachomatis.Trichomonis Vaginalis (protozoa).Treponeum Palladeum (syphillus).Mycoplasma Genitalium.
what kind of bacteria is gonrorrhea?
GN diplicocci
consequences of gonorrhea in pregnany?
neonatal gonococcal opthalmia. Purulent conjunctivitis. Can lead to blidness
treatment for gonorrhea?
ceftriaxone (500 mg IV/IM) and azythromycin
serovars of Clamydia?
A-C trachoma in eye.D-K genital Infection.
clamydia an neonate?
haemorrhagic conjunctivitis and pneumonia
what is trichmonas vaginalis? hallmark symptom?
protozoa. frothy yellow-green vaginal discharge
symptoms of syphillus.
Primary: chancre.Secondary: rash or alapaecia.Tertiary (10-30 years later): gummas, cardiac or neruoligcal pathology
which cell type produces testosterone?
leydig cell
cells of the seminiferous tubules?
sertoli, leydig and spermatagonium
describe the difference in cervical mucus from the ovulation phase to the luteal phase
ovulation = abundant, clear non viscus mucusLuteal = thick, sticky mucous
describe 2 positive feedbacks cycle during menstruation?
in early to mid-follicular phase estorgen positive feedback on granulosa cells.In late follicular phase and ovulation Estrogen positive on GnRH.
