shibbidy Bop

Question 1

What are the 4 Hypoglycaemics?

Answer 1

Biguanides, Sulfonylureas, Thiazolidinediones, Acrabose

Question 2

Types of insulin (name 5)

Answer 2

Ultra-rapid acting – Lispro (Humalog), Aspart (NovoLog). Short duration/slower acting – Natural insulin. Intermediate duration – Humulin Neutral Protamine – Hagerdorn (NPH), Lente insulin (Insuvet). Long duration – Ultralente, Glargine. Premixed biphasic insulin – Neutral:isophane. Long acting – Lantus

Question 3

What’s special about omeprazole?

Answer 3

only PPI available for parenteral delivery

Question 4

What is Nystatins mechanism of action?

Answer 4

binds to ergosterol, a major component of the fungal cell membrane. When present in sufficient concentrations, it forms pores in the membrane that lead to K+ leakage, acidification, and death of the fungus.

Question 5

Colchicine mechanism of action

Answer 5

inhibits microtubule polymerization by binding to tubulin, one of the main constituents of microtubules. Availability of tubulin is essential to mitosis, and therefore colchicine effectively functions as a “mitotic poison” or spindle poison.

Question 6

Colchicine s/e

Answer 6

Nausea, Vomiting, Diarreha, abdominal pain, muscle weakness, peripheral neuropathy, high doses: bone marrow damage, anaemia, hair loss.

Question 7

Mechanism of action for Allopurinol

Answer 7

purine analog; it is a structural isomer of hypoxanthine and is an inhibitor of the enzyme xanthine oxidase (which does stuff leading to uric acid production)

Question 8

what is Stevens-Johnsons syndrome?

Answer 8

life threatening skin condition where cell death causes the epidermis to separate from the dermis.

Question 9

what does Mylanta contain?

Answer 9

Aluminium hydroxide – 200 mg Magnesium Hydroxide – 200 mg Simethicone – 20 mg (per 5 ml)

Question 10

why are magnesium and aluminium used together?

Answer 10

to combat magnesiums laxative and aluminiums constipation affect

Question 11

What is Glucagon?

Answer 11

Polypeptide hormone produced by alpha cells in the pancreatic islets.

Question 12

What does Glucagon do?

Answer 12

Increase plasma levels of glucose by breakdown of glycogen (activates hepatic glucose production)

Question 13

Define Glycogenolysis?

Answer 13

Breakdown of glycogen in the liver to recycle glucose

Question 14

Define Glycogenesis

Answer 14

Conversion of glucose to glycogen for storage in the liver

Question 15

What is Glycogen?

Answer 15

Storage form of glucose