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Diabetic Drugs > SGLT2 Inhibitors > Flashcards

SGLT2 Inhibitors Flashcards

1
Q

Common drugs (and class nickname)

A

Nickname: “Gliflozins”
Canagliflozin (Invokana)
Dapagliflozin (Farxiga)

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2
Q

MOA

A

Inhibit SGLT2 transport proteins in proximal convoluted tubule of nephron, decreasing glucose reabsorption, increasing excreted glucose

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3
Q

Contraindications

A

Decreased renal function (GFR

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4
Q

Serious adverse reactions

A

Renal impairment
Ketoacidosis
Orthostatic hypotension
Bladder cancer risk

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5
Q

Common adverse reactions

A

Genital mycotic infections (esp. in women and uncircumcised men)
UTI
Slight increase in urination

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Diabetic Drugs (7 decks)

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