DPP-4 Inhibitors Flashcards
1
Q
Common drugs (and class nickname)
A
Nickname: “Gliptins”
Sitagliptin (Januvia)
Saxagliptin (Onglyza)
Linagliptin (Tradjenta)
2
Q
MOA
A
Slow incretin metabolism
Increase insulin synthesis/release
Decrease glucagon levels
3
Q
Contraindications
A
Caution in pancreatitis risk
4
Q
Serious adverse reactions
A
Pancreatitis (risk low but unknown)
Anaphylaxis and angioedema
5
Q
Common adverse reactions
A
Predisposition to nasopharyngitis and URI