DPP-4 Inhibitors Flashcards

1
Q

Common drugs (and class nickname)

A

Nickname: “Gliptins”
Sitagliptin (Januvia)
Saxagliptin (Onglyza)
Linagliptin (Tradjenta)

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2
Q

MOA

A

Slow incretin metabolism
Increase insulin synthesis/release
Decrease glucagon levels

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3
Q

Contraindications

A

Caution in pancreatitis risk

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4
Q

Serious adverse reactions

A

Pancreatitis (risk low but unknown)

Anaphylaxis and angioedema

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5
Q

Common adverse reactions

A

Predisposition to nasopharyngitis and URI

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