sexual differentiation Flashcards

1
Q

development of gonads from

A

intermediate mesoderm

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2
Q

when do male/female characteristics appear

A

wk6/7

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3
Q

where to primordial germ cells migrate to

A

genital ridges

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4
Q

vas deferens, epidydimus, seminal vesicles comes from

A

Wolffian duct

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5
Q

fallopian tubes and uterus. cervix, upper 1/3 vagina come from

A

mullerian duct (motheran duct)

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6
Q

primordial germ cells become

A

gametes

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7
Q

what sort of cells are semineferous tubules and ovarian follicles

A

mesothelial (leydig, sertoli, thecal, granulosa)

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8
Q

which gene determines maleness

A

SRY

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9
Q

what does sry protein bind with

A

sterogenic factor 1

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10
Q

what do sertoli cells produce

A

Mulleran inhibiting factor/anti-mulleran hormone

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11
Q

what does MIF do

A

degenerate uterus etc

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12
Q

46 XY DSD is caused by

A

mutation in SRY gene

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13
Q

what happens in in 46 XY DSD

A

no puberty primary amenorrhoea
present as female
infertility
no MIF
no testosterone

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14
Q

DHT forms

A

penis, prostate, scrotum

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15
Q

what is the thing which lowers the gonads

A

gubernaculum

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16
Q

what does gubernaculum become in women

A

round ligament

17
Q

who has tunica vaginalis

A

boys

18
Q

what does tunica vaginalis have in it

A

serous fluid to protect testes anteriorly

19
Q

which muscles come down with the testes

A

internal and external oblique

20
Q

what is internal oblique called inside the scrotum

A

cremaster

21
Q

blood supply to ovary

A

anastamosis of uterine and ovarian arteries

22
Q

lpelvic floor muscles

A

levator ani and perineal body