fetus to baby physiological changes Flashcards
what is oxygen level in utero
relatively hypoxic
what is in lungs in utero
amniotic fluid
what promotes surfactant production
thyroid hormones/glucocorticoids
which chanell upregulates to get rid of water in newborn lungs
ENAC sodium chnannel
why babies born by CS more fluid in lungs
not squeezed on the way out
H
G
difference between type 1 and type 2 pneumocytes
type 1 long and lining, type 2 more cuboidal
what is atelectasis
lung collapse
what do you give to premature labour mother
corticosteroids
fetal hb oxygen affinity
VERY HIGH
ductus arteriosus, ductus venosus, foramen ovale close when?
1st 24h post birth
wher edoes blood flow in 2 directiosn in fetus
IVC
what leads to foramne ovale closure
pressure change
why doesn’t blood go to fetal lungs very much
very high resistance
how is ductus arteriosus closed and what does it become
O2 and decreased prstaglandin E2 after birth becomes ligamentum arteriosum
where is ligamentum arteriosum
between aorta and pulmonary artery
how close DA in babies with too wide DA
give NSAIDs - inhibit prostaglandins
what is a “normal” pathology in baby lungs
partial collapses
what does umbilical vein become
ligamentum teres(round ligament) - looks like little bit at bottom of falciform lig
how non-shivering thermogenesis stimulated
ardenaline
what injection babies at birth
vit k
why jaundice
insoluble bilirubin
how fix jaundice
blue light - makes bilirubin soluble
