Sex Detemination Etc Flashcards
What is a sexual founder
The progeny is made up of half and half of the parents
What are the immediate benefits of sex
Increase in fitness
AIDS repair of deleterious mutations
Bi parental care
What are the long term benefits of sex
Beneficial combinations of alleles
Breaks up deleterious ones
Reduces sibling competition
Produces homo and hetro buffers
How many autosomal chromosome pairs do drosophila have
3
Which gene is turned off to produce males in drosophila
X:A = 0.5. Turns off sex-lethal
How is sex-lethal turned off in males
It’s spliced out
What sex can nematode worms C.elegans be?
Males or homafrodites
What initiates maleness in human?
The SRY gene on the Y chromosome
What does the SRY gene do?
Triggers the development of testies
Encodes protein with DNA binding domain
What animals sex is determined on the environment?
Lizards, reptiles, fish and worms
Why do females have to compensate for dosage of the X chromosome?
Because otherwise they would behave too many genes
What conditions can be produced when gene dosage goes wrong?
Trisomy 21 (Down syndrome) trisomy 18 and 13 which can cause spontaneous abortion and miscarriage
What is haploinsufficency?
Single gene mutations there isn’t enough gene dose (one allele isn’t enough single dosage)
How is the X chromosome shut down in humans
The Barr body shuts down the X chromosome can shut down multiple if an individual has multiple X chromosomes
What is Ohno’s law?
Extremely high conservation of genes on X chromosomes of therian mammals- synteny