Sex and Fertility Flashcards

1
Q

how do sperm mature in the epididymus

A

they begin to be able to move and have the potential to fertilise

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2
Q

what is the sperm maturation in the epididymus dependant on

A

testosterone

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3
Q

what is capacitation

A

where the sperms tail starts to move in a whip like action and its acrosome is lost enabling it to enter the oocyte

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4
Q

what digestive enzyme is found in the sperms acrosome

A

hualronidase

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5
Q

where do the sperm bind on the bona pellucida

A

ZP3 receptor

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6
Q

what makes up the majority of seminal fluid

A

the seminal vesicles

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7
Q

describe the fluid produced by the seminal vesicles

A

it is alkaline, and has fructose

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8
Q

what proportion of the seminal plasma is made by the prostate gland

A

25%

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9
Q

describe the fluid produced by the prostrate gland

A

milky, contains citric acid for calcium ion chelation

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10
Q

what glands produce a very same amount of seminal fluid

A

bulbourethral glands

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11
Q

what is cervical mucus like before ovulation

A

very thin and stretchy due to high oestrogen

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12
Q

what is cervical mucus like after ovulation

A

thick and sticky

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13
Q

where does fertilisation occur

A

in the ampulla of the fallopian tubes

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14
Q

what is a cortical reaction

A

where the oocyte empties its cortical granules - this changes its membrane to stop further sperm from entering

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15
Q

where does implantation occur

A

on the superior, posterior uterine wall

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16
Q

what is placenta preavia

A

where implantation occurs over the internal os

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17
Q

what nervous system causes an erection

A

parasympathetic

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18
Q

through which nerves is an erection initiated

A

the pelvic nerves

19
Q

what does the parasympathetic NS do to cause an erection

A

causes the release of NO which increases arterial dilation, sinusoid relaxation and venous compression

20
Q

true or false: the corpus spongiosum expands in an erection

A

false - this would block the urethra

21
Q

what can cause erectil dysfunction

A

drugs, alcohol, tears in the albuginea

22
Q

what does viagra do

A

slows down the rate of cGMP degrading, os theres more NO giving more blood flow to the penis

23
Q

which nervous system controls ejaculation

A

sympathetic nervous system

24
Q

what is emission

A

contraction of smooth muscle in the vas deferens, prostrate and seminal vesicles to move semen into the prostatic urethra

25
what effect may sympathetic antagonists on ejaculation
they can cause a dry orgasm as they prevent smooth muscle contraction
26
how does the combines oestrogen and progesterone pill work
inhibits ovulations by preventing the LH surge, also inhibits endometrial proliferation and makes the mucus thicker
27
how does the low dose progesterone pill work
does not inhibit ovulation | just makes the cervical mucus thicker
28
how does the intrauterine system work
contains high dose progesterone which inhibits the LH surge as well as thickening mucus and inhibiting endometrial proliferation
29
how does the intrauterine device work
it is made of copper which is toxic to sperm
30
define sub fertility
the failure of conception in a couple having regular, unprotected sex
31
what is primary infertility
where the couple have never conceived before
32
what is secondary infertility
where the couple have conceived before but can't now
33
name some male causes of infertility
``` endocrine such as diabetes, hyperprolactineamia genetic vasculature obstructive STIs drugs ```
34
name some ovulatory causes of infertility
hypothalamic-pituitary failure ovulatory failure hypothalamic-pituitary-ovarian failure
35
give 2 examples of hypothalamic-pituitary-ovarian failure
PCOS | hyperprolactinaemia
36
what is PCOS
where women have too much androgens due to insulin resistance this gives a lack of pulsatile GnRH this causes abnormally high LH and oestrogen causing anolvulation
37
what is anolvulation
where ovulation does always occur
38
what does PCOS stand for
polycystic ovary disorder
39
how do patients with PCOS present
weight gain, increased hair, amenorrhea, infertility
40
what long term consequences of PCOS must you be aware of
developing diabetes due to the insulin resistance | oestrogen causing endometrial malignacies
41
what can be used to treat hyperprolactinemoa
dopamine/bromocriptine
42
what types of uterine damage can cause infertility
fibroids, pelvic inflammatory disease, endometriosis and development abnormalities
43
what types of tubal damage can cause infertility
endometriosis, pelvic surgery or pelvic infections
44
what is assisted reproduction techniques
where the oocytes are fertilised in vitro and allowed to develop into a morula. one of these cells is tested for genetic defects before being inserted into the mother