session_5_flashcards

1
Q

Which of the following conditions is an example of a Polygenic Auto-inflammatory disease?

a. Addison’s disease
b. APS-1
c. Behcet’s syndrome
d. Familial Mediterranean fever
e. Ulcerative colitis

A

Behcet’s syndrome

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2
Q

Which of the following is an example of Gel and Coombs Type 2 hypersensitivity?

a. Anaphylaxis
b. Contact dermatitis
c. Insulin dependent diabetes mellitus
d. Myasthenia gravis
e. Systemic lupus erythematous

A

Myasthenia gravis

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3
Q

A 32 year old male has a productive cough and shortness of breath. His sputum culture was positive for Pneumocystis jiroveci and he is diagnosed with atypical pneumonia. He has a HIV test performed which is positive. A CD4 count is therefore obtained. At what CD4 count would you expect opportunistic diseases to first present?

a. 200 cells/microlitre
b. 400 cells/microlitre
c. 600 cells/microlitre
d. 800 cells/microlitre
e. 1000 cells/microlitre

A

200 cells/microlitre

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4
Q

What is the mechanism of action of corticosteroids?

a. Inhibits calcineurin
b. Inhibits JAK-STAT signalling
c. Inhibits mTOR inhibitors
d. Inhibits PDE4 inhibitors
e. Inhibits phospholipase A2

A

Inhibits phospholipase A2

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5
Q

A 45 year old male presents to his GP with ongoing diarrhoea, weight loss and fatigue. His GP does some blood tests and organises that he has an endoscopy. During his endoscopy the patient has a biopsy done. Pic A shows a normal biopsy from a healthy individual, and pic B shows the results of the biopsy from this patient.
What management would improve his symptoms?

a. Aminosalicylates
b. Corticosteroids
c. Gluten free diet
d. Immunosuppressants
e. Keep a food diary

A

Gluten free diet

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6
Q

A 65 year old male has a 3 month history of melaena, vomiting and 8kg weight loss. After further investigations, he is diagnosed with Stage II gastric cancer. What is the most common type of gastric cancer?

a. Adenocarcinoma
b. Gastrointestinal stromal tumour (GIST)
c. Lymphoma (MALToma)
d. Neuroendocrine tumours
e. Squamous cell carcinoma

A

Adenocarcinoma

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7
Q

A 60 year old female has a urine sample sent for microscopy and culture. This is what you see on microscopy.
What structure is labelled ‘A’?

a. Artefact
b. Erythrocytes
c. Leukocytes
d. Mucus threat
e. Squamous epithelium

A

Erythrocytes

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8
Q

A 80 year old male has a urine sample sent for microscopy and culture. This is what you see on microscopy.
What structure is labelled ‘B’?

a. Artefact
b. Erythrocytes
c. Leukocytes
d. Mucus threat
e. Squamous epithelium

A

Leukocytes

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9
Q

A 40 year old female who received a renal transplant 8 months ago presents to clinic with a generalised pruritic rash. On examination you notice widespread crusting vesicular lesions. What is the most likely causative organism?

A

Varicella Zoster / Herpes Zoster

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10
Q

A 50 year old male has blood tests performed to check his Hepatitis B status. His serological markers show the following: HBsAg negative , anti-HBc negative , anti-HBs positive.
What do his serological markers confirm?

a. Acute infection
b. Chronic infection
c. Immunity secondary to hep B vaccination
d. Immunity secondary to natural infection
e. Resolving acute infection

A

Immunity secondary to hep B vaccination

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