Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

ALL SBAS PATH > histopathology_flashcards > Flashcards

histopathology_flashcards

1
Q

Which is the commonest type of pancreatic neoplasm?

A

Ductal adenocarcinomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which of the following are causes of chronic pancreatitis?

A

All of the above

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

The following are complications of gall stones, except?

A

Haemolytic anaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

20yo med student with abnormal LFT’s. High bilirubin of 32 micromol/L (5-17). GGT, ALT, ALP, AST normal. Never drunk alcohol. No PMH. Cousin had 1 episode of jaundice. What is the next step?

A

Do nothing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which is the most representative of liver function in an acute situation?

A

Prothrombin time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which of these is the commonest carcinoma seen in the liver?

A

Metastatic adenocarcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which of these is not associated with fatty change in the liver?

A

Hepatitis B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which of these is not associated with genetic haemochromatosis?

A

Kayser-Fleisher rings

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Lichen planus is an example of which type of inflammatory reaction pattern?

A

Lichenoid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Where is the epidermis does the bullae in pemphigus vulgaris form?

A

Stratum spinosum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

White/slivery plaques on extensor surfaces are seen in which dermatological condition?

A

Psoriasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The Breslow thickness is used to stage which skin cancer?

A

Malignant melanoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which common skin cancer does not metastasise?

A

Basal cell carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What percentage of lung cancers in the UK develop in non-smokers?

A

10-20%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

I’ve been smoking for 30 years. Stopping now is not going to reduce by risk of lung cancer.

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What does cytopathology code ‘C5’ denote?

A

Malignant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What benign lesions most commonly mimic breast cancer on radiology?

A

Fat necrosis and radial scar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the most common malignant breast tumour?

A

Ductal carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

How many parameters are included in breast tumour grading?

A

3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Impaired blood supply to the bowel most commonly causes what?

A

Ischaemic colitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

A patchy inflammatory bowel condition affecting the stomach, small bowel, and colon is most likely to be what?

A

Crohns disease

22
Q

What sort of colon polyps most commonly predispose to adenocarcinoma of the colon?

A

Adenoma

23
Q

A 76yo man presents with rectal bleeding. The diagnosis that must be excluded first is what?

A

Colorectal carcinoma

24
Q

Causes of granulomatous inflammation in the liver include:

A

TB, Sarcoid, PBC, Drugs, Schistosomiasis, Malignancy

25
Q

The different types of liver damage, due to alcohol, include:

A

Steatosis, Steatohepatitis, Fibrosis, Cirrhosis, Malignancy

26
Q

What type of amyloid is associated with multiple myeloma?

A

AL

27
Q

Most oesophageal and gastric cancers arise from pre-existing adenomas. True or false?

A

False

28
Q

In a patient with coeliac disease on a diet containing gluten, the following is the most likely histological change in the duodenum:

A

Villous atrophy, increased intra-epithelial lymphocytes

29
Q

Which of the following is not a cause of chronic gastritis?

A

Metabolic disease

30
Q

What is the most common brain tumour in adults?

A

Metastatic deposit

31
Q

What is the most common brain tumour in children?

A

Pilocytic astrocytoma

32
Q

What does tumour grade tell us?

A

Survival

33
Q

Which mutation identifies diffuse astrocytic tumours with a better prognosis?

A

IDH mutation

34
Q

45 year old female. PMH: Pulmonary lobectomy. 2 days of headache and vomiting. Worsening headache. CT: Right frontoparietal SOL with minimal midline shift to the left. What is your diagnosis?

A

Metastatic carcinoma

35
Q

70 year old male. Seizure following 2 weeks of left arm and leg weakness. MRI showing heterogeneous enhancing right frontal lesion, started on steroids. Partial response to steroids with improved dexterity of the left arm and leg. A tumour was partially resected. What is your diagnosis?

A

Glioblastoma (WHO grade IV)

36
Q

5 year-old boy. Had headache and vomiting in the morning for 2 weeks. Symptoms worsened and the vision became blurred. Fundoscopic exam: papilledema. MRI showing cystic cerebellar lesion. A tumour was removed. What is your diagnosis?

A

Pilocytic astrocytoma (WHO grade I)

37
Q

When the integrity of the blood brain barrier is disrupted, the result oedema is described as..?

A

Vasogenic

38
Q

Which of the following types of herniation does not involve the cerebral cortex?

A

Tonsillar

39
Q

What percentage of patients who experience a TIA will get a significant infarct within 5 years?

A

33

40
Q

What is the most common cause of non-traumatic intraparenchymal haemorrhages?

A

Hypertension

41
Q

Which of the following is not a prion disease?

A

Huntington’s

42
Q

Tau immunostaining in the peristriate but not the striate cortex is consistent with which Braak grading?

A

IV

43
Q

Excluding Parkinson’s disease, which other disorder (often presenting with Parkinsonism) is associated with alpha-synuclein pathology?

A

Multiple system atrophy

44
Q

Which if the following proteins is not associated with frontotemporal dementia?

A

APP

45
Q

Which of the following is NOT a major risk factor for ischaemic heart disease?

A

High alcohol consumption

46
Q

The major cause of ischaemic heart disease is:

A

Reduced blood flow due to atherosclerosis

47
Q

A common cause of aneurysms is:

A

Hypertension

48
Q

What is the most common cause of thyroid cancer?

A

Papillary

49
Q

What type of thyroid carcinoma arises from the parafollicular C cells of the thyroid?

A

Medullary

50
Q

What syndrome is caused by an adrenal adenoma that secreted aldosterone?

A

Conn’s

51
Q

What cancers are screening for in the UK?

A

Breast, bowel, cervical

52
Q

Which part of the female genital tract is the commonest site to receive metastatic tumours?

A

Ovaries

ALL SBAS PATH (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions