Serous Fluid Flashcards
All body cavities are lined by a thin membrane which has 2 parts:
Visceral membrane
Partial membrane
Is an ultra filtrate of plasma derived from the capillary network of the membrane.
Serous fluid
Formed under the influence of:
- Hydrostatic pressure
- Oncotic pressure
- Capillary permeability.
Any alteration in the rate of formation or removal can cause _______ (accumulation of fluid in the cavity)
Effusion
Causes of Effusion:
Increase hydrostatic pressure
Decreased oncotic pressure (low protein)
Lymphatic obstruction (filariasis, tumors)
MECHANISM:
•Disruption of fluid filtration & absorption
•No direct involvement of the membrane
Transudate
Cause of transudate
Congestive heart failure
Hyponatremia
MECHANISM:
•Direct involvement and injury to the membrane
Exudate
Cause of exudate
Infection and malignancy in membrane
Type of cells of transudate
Lymphocyte
Type of cells exudate
Segmenters
Color of transudate
Light yellow to straw
Color of exudate
Darker, sometimes orange red
Specific gravity of transudate
Less than 1.018
Specific gravity of exudate
More than 1.018
Orgin of transudate
Noninflammatory
Origin of exudate
Inflammatory
LDH of transudate
Less than 550 unit
LDH pf exudate
More than 550 unit
Appearance of transudate
Clear
Appearance of exudate
Cloudy
SPECIMEN COLLECTION used in pleural
Thoracentesis
SPECIMEN COLLECTION: pericardial
Pericardiocentesis
SPECIMEN COLLECTION used in peritoneal
Paracentesis
ANTICOAGULANTS:
EDTA - cell count
Heparin - micro and cyto
Plain tubes- chem
Fluid in the lung cavity
Pleural fluid
Color of pleural fluid
clear or pale yellow fluid.
The fluid surrounding the heart
Pericardial fluid
Color of pericardial fluid
clear and pale yellow
Causes of Pericardial Effusion
Cardiac tamponade
Uremic
Pericarditis
Fluid in the abdominal cavity
Peritoneal fluid
Color of peritoneal fluid
Clear or pale yellow
Access in peritoneal fluid is a condition called
Ascites
Done in cases blunt abdominal injury to detect intra- abdominal bleeding.
Peritonial lavage
Peritonial Lavage Done in cases blunt abdominal injury to detect
Intra-abdominal bleeding
Lab test peritoneal: GIT malignancy
CEA
Lab test peritoneal: Decreased in tubular
Glucose
Lab test peritoneal: High in pancreatitis, GIT perforation
Amylase
Lab test peritoneal: ovarian malignancy
CA125
Lab test peritoneal: breast cancer
CA 153
Lab test peritoneal: pancreatic malignancy
CA 19-9
Lab test peritoneal: GIT PERFORATION
Alkaline phosphate
Lab test peritoneal: ruptures bladder
BUN & creatinine
Transudate peritoneal
• Hepatic cirrhosis (no albumin)
• Hyponatremia (renal or hepatic)
• Congestive Heart Failure
Exudate peritoneal
• Peritonitis
• Appendicitis (ruptured)
• Rupture viscus (hollow organ)
• Malignancy
Chylous effusion: cause
Thoracic duct leakage
Chylous effusion: appereance
Milky/ white
Chylous effusion: leukocytes
predominantly leukocytes
Chylous effusion: cholesterol
Absent
Chylous effusion sudan 3
Strongly positive
Pseudochylous effusion: cause
Chronic inflammation
Pseudochylous effusion: appearance
Milky/green tinge
Pseudochylous effusion: leukocyte
Mixed cells
Pseudochylous effusion: cholesterol
Present
Pseudochylous effusion: sudan 3
Negatively/weakly positive