Serotonin

Question 1

CYPROHEPTADINE

Answer 1

Targets 5-HT2A
Also a muscarinic H1 antagonist
Treat Carcinoid Syndrome and cold-induced urticaria

Question 2

Targets 5-HT2A and Alpha Adrenergics
Block sm contraction and platelet aggregation
Not approved for US use

Answer 2

KETANSERIN

Question 3

TRIPTANS

Answer 3

Agonist - Targets 5-HT1B/D

Prevent vasodilation and stretching of pain fibers, Inhibit pro-inflammatory molecules

Question 4

Targets 5-HT3

(Zofran) Post-surgical/chemo anti-emetic

Answer 4

ONDANSETRON, GRANISETRON

Question 5

BUSPIRONE

Answer 5

Agonist - Targets 5-HT1A

Anxiolytic

Question 6

CLOZAPINE

Answer 6

Targets 5-HT7
(And Dopamine receptors)
Atypical antipsychotic

Question 7

KETANSERIN

Answer 7

Targets 5-HT2A and Alpha Adrenergics
Block sm contraction and platelet aggregation
Not approved for US use

Question 8

Targets 5-HT7
(And Dopamine receptors)
Atypical antipsychotic

Answer 8

CLOZAPINE

Question 9

Agonist - Targets 5-HT1A

Anxiolytic

Answer 9

BUSPIRONE

Question 10

ONDANSETRON, GRANISETRON

Answer 10

Targets 5-HT3

(Zofran) Post-surgical/chemo anti-emetic

Question 11

Agonist - Targets 5-HT1B/D

Prevent vasodilation and stretching of pain fibers, Inhibit pro-inflammatory molecules

Answer 11

TRIPTANS

Question 12

Targets 5-HT2A
Also a muscarinic H1 antagonist
Treat Carcinoid Syndrome, Cold-induced urticaria, Serotonin Syndrom

Answer 12

CYPROHEPTADINE

Question 13

Triphasic Response of Serotonin

Answer 13

Decrease BP/CO/HR, Increase BP, Decrease BP