Serotonin Flashcards
1
Q
Synonym For:
SEROTONIN
A
5 - Hydroxytryptamine
2
Q
The highest concentrations of DA are found in the
A
Brain
3
Q
- Concentrates amines in intracellular storage vesicles (non specific amine carrier)
- it is inhibited by (ans: drug)
A
- VMAT2 (vesicular monoamine transporter)
- Reserpine
4
Q
Drug:
RESERPINE
A
- selectively inhibits VMAT2
- used as antihypertensive and antipsychotic agent
5
Q
Actively transports essential AA in the Brain
A
L-type Amino Acid Transporter 1
(LAT1)
6
Q
The rate limiting enzyme for 5-HT synthesis
A
Tryptophan hydroxylase (TPH)
7
Q
Responsible for the uptake of newly released 5HT
A
SERT
(Serotonin Transporter)
8
Q
MAO-A preferentially metabolizes ()
A
5HT and NE
9
Q
First Generation Antidepressants
A
MAO-A Inhibitors
10
Q
Preferentially metabolizes beta - phenylethylamine and benzylamine
A
MAO-B
low dose selegiline is a relatively selective inhibitor of MAO-B
DA and tryptamine are metabolized equally by both MAO-A and MAO-B
11
Q
A
11
Q
A
