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MT101 > Serology-immunology > Flashcards

Serology-immunology Flashcards

1
Q

study of all the aspects of the immune system, including its structure and function.

A

Immunology

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2
Q

A branch of biomedical science that deals with the response of an organism to antigenic challenge and its recognition of what is self and non-self

A

Immunology

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3
Q

Division of immunology that specializes in the laboratory detection and measurement of antigens and antibodies

A

Serology

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4
Q

A term used to describe the aggregation of particulate test antigens to form larger complexes when specific antibodies are present

A

Agglutination

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5
Q

Two stages of agglutination

A

Sensitization
Lattice Formation

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6
Q

Represents the physical attachment of antibody molecules to antigens

A

Sensitization

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7
Q

the establishment of crosslinks between sensitized particles and antibodies, resulting in aggregation

A

Lattice Formation

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8
Q

Occurs when antigens are found naturally on a particle

A

Direct agglutination

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9
Q

Uses particles that are coated with antigens not normally found on their surfaces

A

Passive/indirect agglutination

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10
Q

uses carries particles attached to antibody rather than antigens

A

Reverse passive agglutination

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11
Q

Based on the competition between particulate and soluble antigens for limited antibody-combining sites
in this type, the agglutination indicates a positive result

A

Agglutination inhibition

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12
Q

Refers to the aggregation of soluble test antigens with soluble antibodies to produce visible insoluble complexes

A

Precipitation

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13
Q

How can precipitation be measured

A

by light scattering using turbidimetry and nephelometry.

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14
Q

A midway reaction between agglutination and precipitation
A process of contact and adhesion where dispersed molecules are held together by weak physical interactions

A

Flocculation

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15
Q

Is a reaction in which the specific antibody has a capacity to nullify/neutralize the reactive effect of a particular antigen

A

Neutralization

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16
Q

The substance that is measured in the laboratory is called

A

Analyte

17
Q

are developed to measure antigens or antibodies that may be small In size or present in low concentrations

A

Labeled Immunoassays

18
Q

Uses radioactive labels such as iodine-131, iodine-125, and tritiated hydrogen

A

Radioimmunoassay

19
Q

Utilizes enzymes such as horseradish peroxidase, glucose-6-phosphate dehydrogenase, alkaline phosphatase and B-D-galactosidase as labels

A

Enzyme immunoassay

20
Q

are naturally occurring molecules that catalyze certain biochemical reactions

A

Enzymes

21
Q

Employs fluorophores or fluorochromes as tags/labels

A

Fluorescent Immunoassay

22
Q

Makes use of chemiluminescent compounds

A

Chemiluminescent Immunoassay

23
Q

are procedures done in the laboratory to determine bacterial infections associated with persistent fever.

A

Bacterial agglutination tests

24
Q

Specific test for typhoid fever

A

Widal test

25
Q

non-specific test for typhus fever

A

Weil-Felix test

26
Q

Diagnostic test for streptococcal infections

A

ASO (Antistreptolysin O) test

27
Q

Non-specific tests for syphilis

A

RPR (Rapid plasma reagin) slide test

28
Q

Specific test for syphilis

A

TPHA (Treponema pallidum hemagglutination assay) test

29
Q

Non specific marker for inflammantion/infection

A

C-RP (C-reactive protein) latex test

30
Q

Non-specific marker for inflammation/infection

A

C3c radioimmunodiffusion (RID) test

31
Q

It is used to determine the presumptive titer of the heterophile antibodies

A

Paul-Bunnell test

32
Q

Classical reference method for the diagnosis of infectious mononucleosis

A

Davidsohn differential test

MT101 (6 decks)

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