Laboratory biosafety and biosecurity

Question 1

The containment principles, technologies, and practices that are implemented to prevent unintentional exposure to pathogens and toxin.
Protects the people from the pathogens

Answer 1

Biosafety

Question 2

The protection, control, and accountability for valuable biological materials within laboratories, in order to prevent their unauthorized access, loss, theft, misuse, diversion, or intentional release
Protects the pathogens from the people

Answer 2

Biosecurity

Question 3

Microorganisms that are unlikely to cause human or animal disease

Answer 3

Risk Group 1

Question 4

Risk group 1

Answer 4

Low individual risk, low community risk

Question 5

Microorganisms that are unlikely to be a significant risk to laboratory workers and the community, livestock, or the environment.

Laboratory exposure may cause infection

Answer 5

Risk group 2

Question 6

Risk group 2

Answer 6

Moderate individual risk, Limited community risk

Question 7

Risk group 3

Answer 7

High individual risk, Limited to moderate community risk

Question 8

Microorganisms that are known to cause serious disease to humans or animals and may present significant risk to lab workers

Answer 8

Risk group 3

Question 9

Risk group 4

Answer 9

High individual risk, High community risk

Question 10

-Microorganisms that are known to produce life-threatening disease to humans or animals
-Represents a significant risk to laboratory workers.

Answer 10

Risk group 4

Question 11

under what biosafety level are bacillus subtilis, naegleria gruberi, infectious canine hepatitis virus?

Answer 11

Biosafety level 1

Question 12

Suitable for work involving microorganisms that are defined and well-characterized strains known not to cause disease in humans

Most appropriate among undergraduate and secondary educational training and teaching laboratories

Answer 12

Biosafety level 1

Question 13

under what biosafety level are hepatitis B virus, Salmonella species, and toxoplasma species?

Answer 13

Biosafety level 2

Question 14

Laboratories that deal with indigenous moderate-risk agents present in the community

Observes practices, equipment, and facility design that are applicable to clinical, diagnostic, and teaching laboratories consequently observing good microbiological techniques

Answer 14

Biosafety level 2

Question 15

Under what biosafety level are mycobacterium tuberculosis, St, Louis encephalitis virus, and Coxiella?

Answer 15

Biosafety level 3

Question 16

Emphasis on primary and secondary barriers in the protection of the personnel, the community, and the environment from infectious aerosol exposure
Work with indigenous or exotic agents with a potential for respiratory transmission, and that may cause serious and potentially lethal infection are being conducted in this level

Answer 16

Biosafety level 3

Question 17

Required for work with dangerous and exotic agents that poses high individual risk of life-threatening diseases that may be transmitted via the aerosol route, for which there are no available vaccines of treatment
Specific practices, safety equipment, and appropriate facility design and construction are required

Answer 17

Biosafety level 4

Question 18

Under what biosafety level are Marburg virus, Cream-Congo hemorrhagic fever

Answer 18

Biosafety Level 4

Question 19

Risk associated to biological toxins or infectious agents

Answer 19

Biorisk

Question 20

Integration of biosafety and biosecurity to manage risks when working with biological toxins and infectious agents

Answer 20

CWA 15793 Laboratory Biorisk Management standard

Question 21

A system or process to control safety and security risks associated with the handling or storage and disposal of biological agents and toxins in laboratories and facilities

Answer 21

CEN Workshop Agreement 15793:2011:

Question 22

Three components of biorisk management

Answer 22

Assessment
Mitigation
Performance

Question 23

Anything in the environment that has the potential to cause harm

Answer 23

Hazard

Question 24

Possibility that something bad or unpleasant will happen

Answer 24

Risk

Question 25

For risk to occur, there must be a _________ for the hazard to cause harm

Answer 25

Situation

Question 26

Risk assessment process

Answer 26

Define the situation
Define the risks
Characterize the risks
Determine if risks are acceptable or not

Question 27

Actions and control measures that are put into place to reduce or eliminate the risks associated with biological agents and toxins

Answer 27

Mitigation procedures

Question 28

Hierarchy of Controls; from most effective to the least effective:

Answer 28

Elimination
Substitution
Engineering controls
Administrative controls
PPE

Question 29

Most difficult and most effective control measure
Total decision of not to work with a specific biological agent or even not doing the intended work

Answer 29

Elimination

Question 30

Replacement of the procedures or biological agent with a similar entity in order to reduce the risk

Answer 30

Substitution

Question 31

Physical changes in workstations, equipment, production facilities or any other relevant aspect of the work environment that can reduce or prevent exposure to hazards

Answer 31

Engineering Controls

Question 32

Policies, standards, and guidelines used to control risks

Practices and procedures comprise minimizing splashes, sprays, and aerosols to avoid laboratory-acquired infections or following standard operating procedures

Answer 32

Administrative controls

Question 33

Devices were worn by workers to protect them against chemicals, toxins, and pathogenic hazards in the laboratory
Least effective measure as it only protects the person who is wearing it, and only when it is used correctly

Answer 33

Personal Protective Equipment