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1. CLASP Sepsis > Sepsis basic principles > Flashcards

Sepsis basic principles Flashcards

1
Q

What is the basic diagnostic criteria for sepsis?

A

News >5 plus evidence of infection

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2
Q

What is the mortality rate for sepsis?

A

10%

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3
Q

How does organ dysfunction occur in sepsis?

A

bacteria enters the blood and the capillaries get leaky leading to organ dysfunction

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4
Q

What is septic shock?

A

hypotension despite fluid resucitation and vasopressors, lactate >2

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5
Q

What is the mortality of septic shock?

A

40%

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6
Q

What do you Take 3 and Give 3 of?

A

Take: blood, urine, lactate
Give: fluids, antibiotics, oxygen

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7
Q

What is the timeframe that the sepsis 6 must be delivered by?

A

1 hour

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8
Q

What sats of oxygen should be delivered? What about for COPD?

A

94-98%

88-92% for COPD

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9
Q

How many blood cultures should be taken?

A

3

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10
Q

How many mls of fluids should be given?

A

500mls bolus of 0.9% saline

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11
Q

What MAP should be aimed for?

A

> 65mmHg

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12
Q

What would a high lactate suggest?

A

hypoperfusion and hypotension

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13
Q

What should be given if still a low BP/lactate >4 after fluids?

A

vasopressors - noradrenaline

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14
Q

What do you do if noradrenaline is not working?

A

refer to ICU for vasopressin

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15
Q

What is the target urine output?

A

0.5ml/kg/hour

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16
Q

What are the typical organsims on Dukes criteria?

A

staphylcoccus aureus
enterococcus faecalis
viridens strep
HACEK group organisms

17
Q

How is C.diff determined?

A

stool toxin test

18
Q

What is the classical presentation of E.coli?

A

bloody diarrhea and petting zoo

19
Q

How is E.coli treated?

A

avoid antibiotics because of HUS

20
Q

What type of organism if Baccilus cereus?

A

gram positive organism

21
Q

What are the empircal IV antibiotics for sepsis?

A

IV amox, metronidazole and gentamicin

22
Q

What percentage of the population have a type 1 penecillin allergy?

A

<0.5%

23
Q

What commensals are found in the gut?

A

coliforms and anerobes

1. CLASP Sepsis (8 decks)

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