Organ dysfunction Flashcards
1
Q
What happens to the cardiovascular system?
A
widespread vasodilation
2
Q
What happens to the pulmonary system?
A
endothelial injury leading to capillary leak
diffuse alveolar oedema
respiratory failure
3
Q
What happens to the renal system?
A
acute kidney injury
- rise in creatine/urea
4
Q
What happens to the liver?
A
shock liver - increased ALT/AST
sometimes jaundice due to diffuse cerebral hypoperfusion
5
Q
What happens to the CNS?
A
delirium/acute confusion due to cerebral hypoperfusion
6
Q
What is the ABG picture of sepsis?
A
lactic acidosis - due to hypoxia of tissues
7
Q
What are the haemotological affects of sepsis?
A
consumptive coagulopathy due to endothelial dysfunction/platelet aggregation and coagulation cascafe activation
low platelets
low fibrogen
