Sepsis Flashcards

1
Q

Sepsis id what?

A

A syndrome

  • a group of body dysfunctions found together
  • dysfunctions progress together in a predictable delay
  • high mortality rate, variable clinical presentations
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2
Q

Sepsis Compared to Anaphylaxis

A
  • both have initial injury
  • both result in organ dysfunction/cardio collapse
  • anaphylaxis is quick and obvious/sepsis is slow and subtle
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3
Q

SIRS Criteria

A
  • temp <36 C or >38 C
  • HR > 90
  • RR > 20
  • WBC < 4000 or > 12000
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4
Q

Normal Response to Infection

A
  • vasodilation
  • vessel permeability
  • once infection is controlled tissue repairs itself
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5
Q

Risk Factors for Sepsis

A
  • extremes of age
  • developmental delay
  • neuro disorder (Cerebal Palsy)
  • recent surgery
  • pregancy/miscarriage
  • reduced immunity
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6
Q

S/S of Sepsis

A
  • FEVER
  • chills/shaking
  • myalgias/arthralgias
  • n/v
  • flu like symptoms
  • mental status changes
  • increased fatigue/lethargy
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7
Q

Fever may be the most seen symptom but who does not often appear w/ a fever?

A

Elderly

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8
Q

Causes of Sepsis

A
  • pneumonia
  • UTI
  • infection after abdominal surgery
  • skin infections
  • C Diff
  • bacteremia from IV
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9
Q

What to look for to identify sepsis?

A
  • SIRS criteria in vitals
  • shock/dehydration
  • check end-tidal CO2
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10
Q

How to Treat Sepsis

A
  • SpO2 > 92%
  • NRB/CPAP/invasice airway
  • 2 large bore IV
  • 30 ml/kg NS bolus
  • may repeat if lungs remain clear
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11
Q

What medication has been seen to worsen the survival rate from Sepsis?

A

Dopamine

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12
Q

What medication is best for Sepsis?

A
  • IV fluid resuscitation
  • norepinephrine (Levophed)
  • vasopressin
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13
Q

Respiratory Component of Sepsis

A
  • mismatch of oxygen availability to changing needs of organs
  • respiratory failure happens quickly
  • ARDS
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14
Q

Severe Sepsis is the most common cause of what?

A

ARDS

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15
Q

S/S of ARDS

A
  • diffuse rales
  • rhonchi
  • respiratory failure
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16
Q

What is a key development preceding multi-organ failure and death?

A

Global tissue hypoxia

17
Q

Pitfalls of Sepsis

A
  • betablockers block tachycardia
  • altered mentation not recognized as organ failure
  • temps not checked or documented correctly
  • alert fatigue
18
Q

You can not diagnose a patient w/ sepsis until what happens?

A

You diagnose a source

NEED DIAGNOSIS

19
Q

You CAN diagnose SIRS w/o a what?

A

cause

20
Q

To go from severe sepsis to septic shock you have to have had what?

A

Your diagnosed w/ hypotension and you’ve given 30 ml bolus and you are still hypotensive