Sepsis Flashcards
1
Q
Describe the pathophysiology for sepsis (6)
A
- from presence of infection and inflammatory response causing increase HR, temp, resps and lactate levels
- localisation and control of infection in bloodstream
- WBCs activate lymphocytes macrophages and neutrophils
- WBCs release molecules abusing vessels to dilate reducing systemic vascular resistance making blood vessels leaky as fluid goes into tissues so O2 can’t diffuse properly causing tissue hypoxia
- WBCs release enzymes to destroy pathogens but damages RBCs too causing activation o clotting cascade but as widespread damage all clotting factors get used up effecting body coagulation
- more CO2 than O2 in blood bc of poorly perfumes tissues causing metabolic acidosis and lower blood PH
2
Q
Signs and symptoms of sepsis (17)
A
High/low temp Diarrhoea Vomiting Sore throat Abnormal vaginal discharge Wound infection signs Uterine tenderness Rash tachycardia Tachpnoea Hypotension Low O2 SATs Dysuria Reduced FMs Poor placental perfusion Clammy Pale/flushed/pallor
3
Q
Risk factors for sepsis (13)
A
Retained products LSCS PROM Pre-term labour Water birth Wound haematoma Invasive procedures CX suture Impaired immunity Uncontrolled diabetes Exposure to young children Meconium Long labour
4
Q
Causes of sepsis (14)
A
Pre existing medical conditions Lungs/chest cavity Throat Chorioamniocentesis Surgery Urinary tract Breast abcess/tenderness Genital tract poor hygiene Wounds Pneumonia Cellulitis Appendicitis Endogenous strep E. coli staph Exogenous pseudomonias
5
Q
Differential diagnosis for sepsis (6)
A
Flu Upper respiratory tract infection UTI DVT mastitis Endometritis
6
Q
Diana comes into day care after her LSCS 2 days ago complaining of vomiting and feeling like she has the flu what would your management plan be?
A
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