Seminar Pharm - Muscle Relaxants Flashcards

1
Q

primary goal of muscle relaxants is to selectively decrease skeletal muscle blank

A

exitability

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2
Q

primary use of muscle relaxants is to reduce blank

A

muscle spasm

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3
Q

injury usually to muscle, peripheral nerve, tonic contraction in paraspinals, traps, etc

A

muscle spasm

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4
Q

CNS lesions or an exaggerated stretch reflex can cause blank

A

spasticity

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5
Q

two drugs to treat muscle spasm

A

diazepam (valium), polysynaptic inhibitors

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6
Q

polysynaptic inhibitors are a diverse group of drugs that includes blank

A

carisoprodol

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7
Q

polysynaptic inhibitors act on polysynaptic reflex arc in spinal cord, and reduce excitatory input to blank

A

alpha motor neuron

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8
Q

polysynaptic inhibitors also cause blank

A

sedation

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9
Q

polysynaptic inhibitors examples

A

soma, vanadom, maolate, paraflex, flexeril, skelaxin, carbacot, antiflex, norflex

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10
Q

valium was originally for blank

A

antianxiety

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11
Q

valium works in the CNS and increases inhibitory effects of blank

A

gaba

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12
Q

gaba allows blank entry

A

Cl-

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13
Q

absense of all sensations

A

general anesthesia

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14
Q

first use of anesthesia after 1846

A

ether (less toxic drugs)

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15
Q

stages of anesthesia

A

analgesia, excitement, surgical, medullary paralysis

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16
Q

2 types of general anesthetics

A

inhalation, intravenous

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17
Q

inhalation agent that is laughing gas

A

nitrous oxide

18
Q

general anesthetics increase blank throughout cns

A

inhibition

19
Q

general anesthetics work by having a direct effect on the blank

A

lipid bilayer/protein ion channels

20
Q

general anesthetics have a combination of blank and blank receptor effects

A

lipid, protein

21
Q

preanesthetic meds and nmj blockers are anesthetic blank

A

adjuvants

22
Q

sedatives, opiods, antimetics are blank meds

A

preanesthetic

23
Q

curare and succinylcholine are blank

A

nmj blockers

24
Q

patitent may remain conscious but indifferent to surroundings during this anesthesia

A

dissociative

25
Q

dissociative anesthesia is achieved with a combo of blank and blank

A

antipsychotic, opiod

26
Q

dissociative anesthesia is useful for these thigns

A

diagnostic imaging, emergency surgeries, dressing changes

27
Q

general anesthetics may be used during blank

A

debridement/changing dressing

28
Q

interrupts nerve conduction at site of application

A

local anesthesia

29
Q

local anesthesia prevents or relieves pain without loss of blank

A

consciousness/systemic effects

30
Q

suffix of local anesthetics

A

-caine

31
Q

local anesthetics bind to blank channels in the nerve membrane, which ruins the chance for blank

A

sodium, ap

32
Q

administration outside of dura

A

epidural

33
Q

administration of anesthetic into subarachnoid space

A

spinal

34
Q

this is done in patients with complex regional pain syndrome

A

sympathetic block

35
Q

when anesthetic is injected into venous system of affected arm or leg

A

bier (iv) block

36
Q

iv block requires a blank placed proximally to keep drug in limb

A

tourniquet

37
Q

small catheter is implanted near peripheral nerve to a specific region and local anesthetic is dripped slowly onto nerve

A

continuous nerve block

38
Q

continuous nerve block is for blank pain control

A

post op

39
Q

continuous nerve block example is inserting catheter near femoral nerve for post op pain after blank

A

total knee

40
Q

smallest, unmyelinated fibers affected first in this nerve block

A

differential

41
Q

order of functional loss for differential nerve block

A

pain, temp, touch, proprioception, motor