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Pharmacology > Semester 2 Exam II Drugs > Flashcards

Semester 2 Exam II Drugs Flashcards

1
Q

Levodopa

A

Dopaminergic agent; precursor in dopamine synthesis, crossed BBB

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2
Q

Carbidopa

A

Decarboxylation inhibitor (never monotherapy)

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3
Q

Carbidopa/levodopa (Sinemet)

A

Preferred Parkinson’s treatment

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4
Q

Bromocriptine

A

Ergot dopamine agonist

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5
Q

Ropinirole

A

Non-ergot dopamine agonist (Parkinson’s or restless leg)

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6
Q

Pramipexole

A

Non-ergot dopamine agonist (Parkinson’s or restless leg)

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7
Q

Selegiline

A

Monoamine oxidase type B inhibitor (always use with sinemet)

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8
Q

Rasagiline

A

Monoamine oxidase type B inhibitor (always use with sinemet)

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9
Q

Amantadine

A

Alternative to MAO-B inhibitor

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10
Q

Entacapone

A

COMT inhibitor (always with sinemet)

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11
Q

Tolcapone

A

COMT inhibitor (always with sinemet)

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12
Q

Pimavanserin

A

Atypical antipsychotic (only for Parkinson’s associated psychosis)

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13
Q

Tetrabenazine

A

VMAT-2 inhibitor (for chorea management)

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14
Q

Propranolol

A

Beta blocker (for essential tremor)

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15
Q

Atenolol

A

Beta blocker (for essential tremor)

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16
Q

Nadolol

A

Beta blocker (for essential tremor)

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17
Q

Metoprolol

A

Beta blocker (for essential tremor)

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18
Q

Primidone

A

Anticonvulsant (best choice for essential tremor)

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19
Q

Gabapentin

A

Anticonvulsant (essential tremor)

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20
Q

Topiramate

A

Anticonvulsant (essential tremor)

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21
Q

Interferon beta-1a

A

Interferon (MS) (SC)

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22
Q

Interferon beta-1b

A

Interferon (MS) (SC)

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23
Q

Glatiramer acetate

A

Immunomodulator for MS (daily SC)

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24
Q

Fingolimod

A

Immunomodulator for MS (PO)

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25
Q

Teriflunomide

A

Immunomodulator for MS (PO)

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26
Q

Dimethyl fumarate

A

Immunomodulator for MS (PO)

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27
Q

Ocrelizumab

A

Monoclonal antibody for MS (IV)

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28
Q

Natalizumab

A

Monoclonal antibody for MS (IV)

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29
Q

Penicillin VK

A

Naturally occurring penicillin (beta lactam)

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30
Q

Penicillin G

A

Naturally occurring penicillin (beta lactam)

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31
Q

Amoxicillin

A

Aminopenicillin (beta lactam)

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32
Q

Amplicillin

A

Aminopenicillin (beta lactam)

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33
Q

Dicloxacillin

A

Penicillinase-resistant penicillin (beta lactam)

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34
Q

Nafcillin

A

Penicillinase-resistant penicillin (beta lactam)

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35
Q

Oxacillin

A

Penicillinase-resistant penicillin (beta lactam)

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36
Q

Piperacillin

A

Antipseudomonal penicillin (beta lactam)

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37
Q

Ampicillin/subactam

A

Beta-lactamase/penicillin combo

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38
Q

Amoxicillin/clavulanic acid

A

Beta-lactamase/penicillin combo

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39
Q

Piperacillin/tazobactam

A

Beta-lactamase/penicillin combo (antipseudomonal) - Zosyn

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40
Q

Ticarcillin/clavulante

A

Beta-lactamase/penicillin combo (antipseudomonal)

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41
Q

Cefazolin, Cephalexin, Cefadroxil

A

1st generation cephalosporins (beta lactam)

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42
Q

Cefaclor, Cefprozil, Cefuroxime, Lorbacef, Cefotetan, Cefoxitin

A

2nd generation cephalosporins (beta lactam)

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43
Q

Cefdinir, Cefixime, Cefpodoxime, Ceftibuten, Cefoperazone, Cefotaxime, Ceftriaxone, Ceftizoxime

A

3rd generation cephalosporins (beta lactam)

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44
Q

Ceftazidime

A

3rd generation cephalosporin (beta lactam) - with pseudomonas coverage

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45
Q

Cefepime

A

4th generation cephalosporin (beta lactam)

46
Q

Ceftaroline

A

5th generation cephalosporin (beta lactam)

47
Q

Ceftazidime/avibactam

A

Cephalosporin/beta-lactamase combo

48
Q

Ceftolozane/tazobactam

A

Cephalosporin/beta-lactamase combo

49
Q

Ertapenem

A

Carbapenem (beta lactam)

50
Q

Imipenem/cilastatin

A

Carbapenem (beta lactam)

51
Q

Meropenem

A

Carbapenem (beta lactam)

52
Q

Doripenem

A

Carbapenem (beta lactam)

53
Q

Meropenem/vaborbactam

A

Carbapenem/beta-lactamase inhibitor

54
Q

Aztreonam

A

Monobactam (beta lactam)

55
Q

Vancomycin

A

Glycopeptide

56
Q

Dalbavancin

A

Glycopeptide

57
Q

Telavancin

A

Glycopeptide

58
Q

Oritavancin

A

Glycopeptide

59
Q

Doxycycline

A

Tetracycline

60
Q

Minocycline

A

Tetracycline

61
Q

Tetracycline

A

Tetracycline

62
Q

Tigecycline

A

Tetracycline

63
Q

Omadacycline

A

Tetracycline

64
Q

Eravacycline

A

Tetracycline

65
Q

Ciprofloxacin

A

Fluoroquinolone

66
Q

Levofloxacin

A

Fluoroquinolone

67
Q

Moxifloxacin

A

Fluoroquinolone

68
Q

Ofloxacin

A

Fluoroquinolone

69
Q

Delafloxacin

A

Fluoroquinolone

70
Q

Azithromycin

A

Macrolide

71
Q

Clarithromycin

A

Macrolide

72
Q

Erythromycin

A

Macrolide

73
Q

Clindamycin

A

Clindamycin (prevent tRNA binding to 50s subunit)

74
Q

Metronidazole

A

Metronidazole (inhibits DNA synthesis by causing strand breakage) - C. diff tx. (Flagyl)

75
Q

Sulfamethoxazole/trimethoprim

A

Bactrim; sulfamethoxazole –> dihydropteroate synthase, trimethoprim –> dihydrofolate reductase

76
Q

Amikacin

A

Aminoglycoside

77
Q

Gentamicin

A

Aminoglycoside

78
Q

Tobramycin

A

Aminoglycoside

79
Q

Plazomicin

A

Aminoglycoside

80
Q

Nitrofurantoin

A

Nitrofurantoin (destroy bacterial DNA and ribosomal proteins)

81
Q

Linezolid

A

Oxazolidinone

82
Q

Tedizolid

A

Oxazolidinone

83
Q

Daptomycin

A

Daptomycin (“punches holes in membrane” binds with calcium and inserts in membrane –> K efflux)

84
Q

Rifampin

A

Rifampin (inhibits RNA polymerase)

85
Q

Fosfomycin

A

Fosfomycin (inhibits MurA enzyme) - one time dose, only for UTI

86
Q

Fidaxomicin

A

Fidaxomicin (binds RNA polymerase, prevents transcription) - C diff tx

87
Q

Terbinafine

A

Allylamine

88
Q

Butenafine

A

Allylamine

89
Q

Naftifine

A

Allylamine

90
Q

Amorolfine

A

Allylamine

91
Q

Ketoconazole

A

Imidazole azole

92
Q

Clotrimazole

A

Imidazole azole

93
Q

Miconazole

A

Imidazole azole

94
Q

Econazole

A

Imidazole azole

95
Q

Mebendazole

A

Imidazole azole

96
Q

Oxiconazole

A

Imidazole azole

97
Q

Sertaconazole

A

Imidazole azole

98
Q

Sulconazole

A

Imidazole azole

99
Q

Thiabendazole

A

Imidazole azole

100
Q

Fluconazole

A

Triazole azole

101
Q

Itraconazole

A

Triazole azole

102
Q

Voriconazole

A

Triazole azole

103
Q

Posaconazole

A

Triazole azole

104
Q

Isavuconazole

A

Triazole azole

105
Q

Nystatin

A

Polyene

106
Q

Amphotericin B

A

Polyene

107
Q

Caspofungin

A

Echinocandin

108
Q

Micafungin

A

Echinocandin

109
Q

Anidulafungin

A

Echinocandin

110
Q

Flucytosine

A

Converted to 5-florouracil by fungi (not monotherapy)

Pharmacology (8 decks)

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