Sem 1 - Intro Flashcards
Using H&E what colour will cell cytoplasm typically stain? why?
Pink. Eosin is negatively charged and cytoplasm is positively charged
The cytoplasm of cells with abundant rough endoplasmic reticulum typically what colour? rough endoplasmic reticulum has affinity for which dye?
purple. All the RNA from the RER will stain blue. As the cytoplasm will normally stain pink due to its positive charge, the mixture of pink and blue will give the cytoplasm a purple appearnce
Nuclei appear basophilic as haematoxylin binds to what?
phosphate groups of nucleic acids
Which epithelial subtype lines the intimal surface of blood vessels and cardiac chambers? What specific name is given to these cells in this situation?
simple squamous. Endothelium
What epithelial subtype lines the pericardial, peritoneal and pleural cavities ie. serous body cavities? What specific name is given to these cells in this situation?
simple squamous. Mesothelium
On what specific structure do epithelial cells (or the basal cells in the case of stratified epithelia) sit?
basement membrane
Which epithelial subtype is best adapted to withstand mechanical abrasion?
stratified squamous
Absorptive cells are most likely to be of which one of the following epithelial subtypes
simple columnar
Adherens junctions and desmosomes use which one of the following transmembrane proteins to bind to adjacent cells
cadherins
components of ECM (5)
Fibrillin Proteoglycans Water Collagen Glycoproteins
4 types of basic tissue?
connective, muscle, nervous, epithelial
What are the 3 main fibre types present in supporting/connective tissue?
Colllagen, Elastin, Reitculin
Basement membrane is predominantly composed of which type of collagen?
4
the dermis contains scattered spindled or elongated nuclei. To what cell type are these likely to belong?
fibroblasts
what does a fibroblast do?
makes ECM and collagen.
