Selection, recirculation, and homing of Lymphocytes

Question 1

White pulp of spleen consists of

Answer 1

• PALS: T-Cell area
• Lymphoid follicles: B-Cell area
• Macrophages and lymphocytes surrouding the Lymphoid follicle

Question 2

Pre-B-Cell marker

Answer 2

Cytoplasmic μ+

Question 3

Paracortex of Lymph node contains

Answer 3

T-cells

Question 4

Outer cortex of Lymph node contains

Answer 4

Follicles (B-cell area)

Question 5

Inner Medulla of Lymph node contains

Answer 5

Macrophages

Question 6

MHC 2 CHX

Answer 6

1. α and β chains
2. Expressed codominantly
3. Present only on APC

Question 7

MHC 1 genes

Answer 7

1. HLA - A
2. HLA - B
3. HLA - C

Question 8

Outer Cortex of Thymus packed with

Answer 8

Immature T-cells

Question 9

MHC 2 genes

Answer 9

1. HLA - DM
2. HLA - DP
3. HLA - DQ
4. HLA - DR

Question 10

Tdt expressed from Pro-B-Cell to

Answer 10

Pre-B-Cell

Question 11

Immature B-Cell marker

Answer 11

Surface IgM

Question 12

What produces self tolerance

Answer 12

Clonal Anergy and Clonal deletion

Question 13

MHC 1 CHX

Answer 13

• α chain plus β₂ microblobulin
• Codominantly expressed
• All Nucleated cells of the body