CD Markers Flashcards

1
Q

CD19 Cellular expression

A

B cells

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2
Q

CD2 (LFA-2) Funciton

A

Adhesion molecule

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3
Q

CD20 Cellular expression

A

B cells

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4
Q

CD18 function

A

Cell adhesion molecule

Missing in Leukocyte Adhesion Deficiency

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5
Q

CD40 Cellular expression

A
  1. B cells
  2. Macrophages
  3. Dendriti cells
  4. Endothelial cells
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6
Q

CD16 (Fc receptor) function

A

Opsonization ADCC

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7
Q

CD18 Cellular expressioin

A

Leukocytes

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8
Q

CD25 Cellular expression

A

Activated TH cells and TReg

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9
Q

CD34 function

A

Cell-cell adhesion

Binds L-selecting

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10
Q

CD21 (CR2, C3d receptor) function

A

Receptor for complement fragment C3d, forms coreceptor complex with CD19

EBV receptor

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11
Q

CD4 function

A

Coreceptor for TCR-MHC2 interaction

Receptor for HIV

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12
Q

CD21 (CR2, C3d receptor) Cellular expression

A

Mature B cells

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13
Q

CD34 Cellular expression

A

Precursors of hematopoietic cells

Endothelial cells in HEV

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14
Q

CD8 Cellular expression

A

CTL

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15
Q

CD3 function

A

Signal transduction by the TCR

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16
Q

CD25 function

A

α chain of IL-2 receptor

17
Q

CD2 (LFA-2) Cellular expression

A
  1. T Cells
  2. Thymocytes
  3. NK cells
18
Q

CD8 funciton

A

Coreceptor for MHC 2

19
Q

CD3 Cellular expression

A
  1. T cells
  2. Thymocytes
20
Q

CD16 (Fc receptor) Cellular expression

A
  1. NK cells
  2. Macrophages
  3. PMN
21
Q

CD14 (LPS receptor) Cellular expression

A
  1. Monocytes
  2. Macrophages
  3. Granulocytes
22
Q

CD19 function

A

Coreceptor for CD21 for B cell activation

23
Q

CD4 Cellular expression

A
  1. TH cells
  2. THymocytes
  3. Monocytes
  4. Macrophages
24
Q

CD14 (LPS receptor) function

A

Binds LPS