Selectin & Integrin Flashcards
1
Q
3 Types of selectins?
A
- L-selectin –> WBC (Neu,Mono,Lymph)
- E-selectin –> Endothelium
- P-selectin –> Endothelium
2
Q
The common ligand of selectin is?
A
Sialyl-Lewis X expressed both on WBCs and epithelium.
3
Q
Both E-selectin and P-selectin activated by TNF and IL-1, which of them activated also by histamine & thrombin?
A
P-selectin. P-אפצ’י-allergy-histamine.
4
Q
C11 and CD18 are integrins. their ligand is:
A
ICAM1 and ICAM2
5
Q
VCAM1 is a ligand for:
A
Integrins CD29 and CD49.
6
Q
Which adhesion molecule characterized by homotypic interaction?
A
CD31 - Ig family protein.
