Select Agents

Question 1

Rift Valley Fever

Answer 1

d

Question 2

Bacillus anthracis General

Answer 2

Bacillus anthracis, is a gram-positive, non-hemolytic, and non-motile bacillus. Most mammals are susceptible to anthrax; it mostly affects herbivores that ingest spores from contaminated soil and, to a lesser extent, carnivores that scavenge on the carcasses of diseased animals. The inhalation infectious dose is within the range of 2,500-55,000 spores. It is believed that very few spores (10 or less) are required for cutaneous anthrax. OCCUPATIONAL INFECTIONS Occupational infections are possible when in contact with contaminated animals, animal products or pure cultures Numerous cases of laboratory-associated anthrax (primarily cutaneous) have been reported.

Question 3

Bacillus anthracis

Answer 3

a

Question 4

Bacillus anthracis Pasteur strain

Answer 4

a

Question 5

Bacillus anthracis Pasteur strain

Answer 5

a

Question 6

Bacillus anthracis NATURAL MODES OF INFECTION

Answer 6

1) cutaneous (via broken skin), 2) gastrointestinal (via ingestion), and 3) inhalation anthrax. Cutaneous anthrax is the most common and readily treatable form of the disease. Inhalation anthrax used to be known as “Woolsorter disease” due to its prevalence in textile mill workers handling wool and other contaminated animal products. While naturally occurring disease is no longer a significant public health problem in the United States, anthrax has become a bioterrorism concern. In 2001, 22 people were diagnosed with anthrax acquired from spores sent through the mail, including 11 cases of inhalation anthrax with five deaths and 11 cutaneous cases.