Practice test questions

Question 1

Toxins:

a) Should be handled as toxic chemicals, rather than biohazards
b) Often have no treatment or vaccine
c) May not be inactivated by autoclaving
d) Are usually environmentally stable

Answer 1

e) All of the above

Question 2

The cloning of genes coding for molecules toxic for vertebrates that have an LD50 of

Answer 2

c) Appendix F of the NIH Guidelines

Question 3

When working with rhesus monkeys, which of the following agents listed
should be considered in the risk assessment?
a) Salmonella, Shigella, Cercopithecine herpesvirus 1
b) Francisella tularensis, Rickettsiae rickettsii
c) Lymphocytic choriomeningitis virus
d) Hepatitis B virus, Hepatitis C virus

Answer 3

a) Salmonella, Shigella, Cercopithecine herpesvirus 1

Question 4

Which of the agents below presents the most risk for plumbers and wastewater treatment employees?

a) Mycobacterium leprae
b) HAV and cryptosporidium
c) HIV and HCV
d) Treponema pallidum and Brucella abortus

Answer 4

b) HAV and cryptosporidium

Question 5

If researchers are handling wild-caught rats, which of the items below should
be considered in the risk assessment?
a) Fleas and potentially plague
b) Rabies
c) LCM
d) Bacillus anthracis
e) All of the above

Answer 5

e) All of the above

Question 6

Organisms that are of increased risk (over the general population) for a
pregnant woman working in a laboratory include:
a) Human parainfluenza viruses
b) Moraxella spp.
c) West Nile Virus
d) Hepatitis E virus and Toxoplasma gondii
e) Streptococcus pneumoniae and HCV virus
f) All of the above

Answer 6

d) Hepatitis E virus and Toxoplasma gondii

Question 7

DURC refers to:

a) Determined Urgency of Research Commitments
b) Doubtful Use of Research Containment
c) Dual Use Research of Concern
d) Differing Use of Risk Containment

Answer 7

c) Dual Use Research of Concern

Question 8

In 2012, two papers for publication drew the attention of the NSABB. What
was the infectious agent in both of these widely debated articles?
a) Bacillus anthracis
b) SARS coronavirus
c) Yersinia pestis
d) Burkholderia mallei
e) Avian influenza virus

Answer 8

e) Avian influenza virus

Question 9

Which of the following statements is NOT true about the risk of a laboratory
working with unknown human blood specimens:
a) Specimens should be handled with universal precautions
b) Specimens may contain indigenous infectious agents
c) Specimens should be handled at a minimum in a BSL-3 facility
d) There may be alternate transmission routes with any agents present
e) The infectious dose may be unknown for any agents present

Answer 9

c) Specimens should be handled at a minimum in a BSL-3 facility

Question 10

Which of the following is the particle size, when produced by a sonicator,
most likely to be inhaled deep into the lung?
a) >50 microns
b) 40-50 microns
c) 20-40 microns
d) <10 microns

Answer 10

d) <10 microns

Question 11

The following classes of hazardous waste generally take precedence over infectious or biomedical waste if mixed:

Hazardous chemicals
Radioactive materials
Both A&B
None of the above

Answer 11

Both A&B

Question 12

Which of the following is true about selection of Personal Protective Equipment (PPE)?

• should be the first line of defense against job hazards
• the exposure determination required by the OSHA BBP Standard should be made after consideration of PPE in use
• selection of PPE should not be generic – use should be observed in specific tasks
• all of the above

Answer 12

selection of PPE should not be generic – use should be observed in specific tasks

Question 13

Regarding glove selection:

• should be task dependent
• latex gloves are generally agreed to be effective against blood-borne pathogens
• latex gloves may not be the best choice for use with -solvents and other chemicals

all of the above

Answer 13

all of the above