Seizures Flashcards

1
Q

What is the term for recurrent unprovoked seizures?

A

Epilepsy

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2
Q

Causes of seizures?

A
  • drug noncompliance
  • metabolic disorders
  • CNS infection
  • head trauma
  • sleep deprivation
  • brain tumors/lesions
  • toxins (drugs, metal poisoning, etc)
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3
Q

What is the term for cortical discharges localized within one cerebral hemisphere?

A

focal seizures

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4
Q

How long do tonic-clonic seizures usually last?

A

2-5 min

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5
Q

what is the term for a series of seizures lasting longer than 5 min with the patient never returning to baseline between the seizures?

A

status epilepticus
- medical emergency
- aggressive tx need is lasts longer than 5 min

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6
Q

what test should be done for a patient suspected of having seizures?

A
  • continuous electroencephalogram (EEG)
  • CT scan
  • MRI scan
  • UA
  • drug screen
  • prolactin (rises 2-3x above norm from appx 1 hr after most tonic-clonic seizures)
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7
Q

What are the meds used to tx generalized convulsive epileticus?

A
  • lorazepam 0.1mg/kg (max 4mg/dose), repeat 1x prn
  • midazolam 0.2mg/kg (max 10mg)
  • diazapam 0.15 mg/kg/dose (max 10mg), repeast 1x prn
  • fosphenytoin 20mg/kg
  • phenytoin 20mg/kg
  • valproic acid 30mg/kg
  • levetiracem 40-60mg/kg over 15 min (max 4500mg)
  • phenobarbitol 20mg/kg
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8
Q

Lorazepam brandname?

A

Ativan

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9
Q

Midazelam brandname?

A

versed

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10
Q

Diazepam brandname?

A

valium

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11
Q

term meaning to have language difficulties that may be cognitive/expressive or receptive?

A

Aphasia

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12
Q

term meaning the inability to perform previously learned movements/tasks or to use objects properly?

A

Apraxia

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13
Q

term for the loss of comprehension of auditory, visual, or other sensations although sensory system is intact?
- inability to recognize objects, shapes, people, sounds, smells, etc.

A

Agnosia

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14
Q

What are the drug treatment options for a patient with moderate Alzheimer’s Disease?

A
  • donepezil (aricept)
  • rivastigmine (execelon)
  • galantamine hydrobromide (Razadyne)
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15
Q

Donepezil (Aricept) is what class of medication?

A

acetylcholinesterase inhibitor
- treatment for Alzheimers and dementia

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16
Q

What are the adverse effects of Donepezil (Aricept)?

A
  • syncope
  • bradycardia
  • AV block (need baseling EKG)
  • nausea
  • diarrhea
  • weight loss
17
Q

What is the treatment for moderate to severe Alzheimer’s Dementia?

A
  • N-methyl-D-aspartate receptor antagonist:
  • Memantine (Namenda)
18
Q

Donepezil (aricept) is used to treat what condition?

A

Mild to moderate alzheimer’s disease

19
Q

Memantine (Namenda) is used to treat what condition?

A

moderate to severe Alzheimer’s disease

20
Q

Olanzapine (zyprexa) is used in the treatment of what conditions?

A
  • schizophrenia
  • bipolar I disorder
  • agitation
21
Q

Quetiapine (Seroquel) is used to treat what conditions?

A
  • anti-psychotic medication
  • schizophrenia
  • bipolar disorder
  • major depressive disorder
22
Q

Quetiapine (Seroquel) is used to treat what conditions?

A
  • anti-psychotic medication
  • schizophrenia
  • bipolar disorder
  • major depressive disorder
23
Q

What is the brand name for Quetiapine?

A

Seroquel

24
Q

What is Seroquel’s MOA?

A
  • dopamine and serotonin antagonist, binds to receptors, resulting in their deactivation
  • used to treat schizophrenia, bipolar, major depression
25
Q

What is Buspirones MOA?

A
  • aka Buspar
  • anti-anxiety med
  • serotonin receptor agonist; activates serotonin receptors
  • does not have sedative, hypnotic or muscle relaxing properties
26
Q

What is Fluoxetine’s brandname?

A

Prozac

27
Q

What is sertraline’s brandname?

A
  • zoloft
  • selective serotonin reuptake inhibitor (SSRI)
  • treats major depressive disorder, social anxiety disorder
28
Q

What is Citalopram’s (celexa) MOA?

A
  • selective serotonin reuptake inhbitor