Immune/Infection

Question 1

Vancomycin is used to treat infections caused by which organisms?

Answer 1

Parentally (IV)
- staphylococcal spp
- streptococcal spp
PO
- Clostridium Dificile (C-Dif)
- staphylococcal spp (including MRSA)

Question 2

How is vancomycin eliminated from the body?

Answer 2

• feces if given PO, poorly absorbed from GIT
• urine if given parentally, not removed by HD

Question 3

What is the half-life for vancomycin?

Answer 3

4-11 hours
- increased in patients with renal insufficiency or impairment

Question 4

What are the most common organisms that cause septic shock?

Answer 4

• staphylcoccus aureus
• streptococcus pneumoniae
• enteric gram-negative bacilli

Question 5

Which empiric antibiotics are recommended to treated septic shock?

Answer 5

Vancomycin plus one of the below:
- piperacillin-tazobactam (zosyn)
- imipenem
- meropenem (merrem)
- cefepine

Question 6

Piperacillin-tazobactam is also known as?

Answer 6

Zosyn

Question 7

What type of bacteria is pseudomonas aeruginosa?

Answer 7

gram-negative aerobic bacillus

Question 8

What class of antibiotic is piperacillin-tazobactam (zosyn)?

Answer 8

• piperacillin = anti-pseudomonal pcn
• tazobactam = beta-lactamase inhibitor

Question 9

Vancomycin is what class of antibiotic?

Answer 9

tricyclic glycopeptide antibiotic
- bactericidal
- inhibits RNA sythesis

Question 10

IV Vancomycin is used to treat which infections caused by which pathogen(s)?

Answer 10

• staphylococcal and streptococcal spp

Question 11

PO Vancomycin is used to treat which type of infections?

Answer 11

• diarrhea associated with aclostridium difficile (C-Dif)
• enterocolitis d/t staphylococcus aureus (including MRSA)

Question 12

IV Vancomycin is used to treat which infection(s)?

Answer 12

• septicemia
• infective endocarditis
• skin and skin structure infections
• bone infections
• lower respiratory tract infections

Question 13

Linezolid is also known as what?

Answer 13

Zyvox

Question 14

Linezolid (Zyvox) is used to treat which infections caused by which pathogen(s)?

Answer 14

gram-positive bacteria
- staphylococcus aureus
- streptococcus pneumoniae
- streptococcus pyogenes
- streptococcus agalactie
- mycoplasma pneumoniae
- chlamydia pneumoniae

Question 15

Which organism(s) are the most common cause(s) of community-acquire pneumonia (CAP)?

Answer 15

• chlamydia pneumia
• haemophilus influenza
• mycoplasma pneumoniae
• streptococcus pneumoniae

Question 16

Which organism(s) are the most common cause(s) of pneumonia a non-ICU patient?

Answer 16

• chlamydia pneumia
• haemophilus influenza
• mycoplasma pneumoniae
• streptococcus pneumoniae
• legionella spp

Question 17

Which organism(s) are the most common cause(s) of pneumonia an ICU patient?

Answer 17

• chlamydia pneumia
• haemophilus influenza
• mycoplasma pneumoniae
• streptococcus pneumoniae
• legionella spp
• staphylococcus aurea

Question 18

What is tissue tropism?

Answer 18

the ability of a pathogen to infect and grow in a specific tissue or cell type of a host

Question 19

What is the term for the ability of a pathogen to infect and grow in a specific tissue or cell type of a host?

Answer 19

tissue tropism