Seizures Flashcards

1
Q

What is an epileptic seizure?

A

Abnormal uncontrollable hypersynchronous activation of a large group of neurons

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2
Q

Define epilepsy

A

Recurrent epileptic seizures

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3
Q

Where are eplipetic seizures localized to in the nervous system?

A

Forebrain neurolocalisation

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4
Q

What are isolated seizures?

A

Seizures that last <5 mins

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5
Q

What are cluster seizures?

A

2 or more seizures in a 24 hours period with complete recovery in-between

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6
Q

What is status epilepticus?

A

Seizure >5 mins
2 seizures without complete recovery inbetween

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7
Q

What is the significance of status epilepticus?

A

Most likely to cause brain damage

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8
Q

What are the three parts of a seizure?

A

Pre-ictal phase
Ictus under
Post-ictal phase

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9
Q

What is the interictal phase?

A

The period of time between two separate seizure events

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10
Q

What are the two types of extra-cranial causes fo seizures?

A

Toxins
Metabolic disease

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11
Q

List three metabolic, extra-cranial causes of seizures.

A

Portosystemic shunt
Hypoglycaemia
Hypocalcaemia

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12
Q

List three structural causes of epilepsy

A

Brain tumour
Inflammation
Hydrocephalus

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13
Q

Between which ages can you make a presumptive diagnosis of idiopathic epilepsy in animals?

A

Between 6 months and 6 years

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14
Q

What are the four types of blood tests used to investigate seizures?

A

Haematology
Serum biochemistry
Fasted blood glucose
Pre + post prandial bile acids

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15
Q

List four occasions where treatment is indicated for idiopathic epilepsy

A

Underlying structural or metabolic cause
Cluster seizures or status epilepticus
If >1 seizure per month
Increasing frequency

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16
Q

What are anti-convulsants used for?

A

Emergency management of seizures

17
Q

List three anti-convulsants

A

Diazepam, midazolam, propofol

18
Q

List four anti-epileptic drugs

A

Phenobarbitone, imepitoin, levetiracetam, KBr