Section III: Cardiovascular Physiology Flashcards
Chapter 18
What is the name of the condition when blood flow to a tissue is inadequate to meet the metabolic needs of the tissue?
a. Anemia
b. Edema
c. Necrosis
d. Ischemia
e. Infarction
D
The volume of blood pumped by the left ventricle in 1 minute would equal:
a. The volume of blood that flowed through the coronary circulation (in the same minute).
b. The volume of blood that flowed through all organs of the systemic circulation, except for coronary blood flow.
c. The volume of blood that flowed through the lungs.
d. One-half of the cardiac output.
e. Two times the cardiac output.
C
A transfusion of normal plasma into a normal dog would:
a. Decrease the hematocrit of the recipient’s blood.
b. Increase the viscosity of the recipient’s blood.
c. Decrease the mean corpuscular hemoglobin concentration (MCHC) in the recipient’s plasma.
d. Increase the number of cells in the recipient’s blood.
e. Decrease the concentration of proteins in the recipient’s plasma.
A
Which of the following sequences of capillary beds might a red blood cell encounter in a normal circulation?
a. Lungs, skin, lungs, brain
b. Spleen, liver, mesentery, lungs
c. Coronary, kidney (glomerular), kidney (tubular), lungs
d. Lungs, coronary, stomach, liver
e. Brain, lungs, liver, coronary
A
The walls of most capillaries have pores or clefts in them, which are approximately 4 nm (4 × 10–9 m) in diameter.
a. A capillary pore is many times larger in diameter than a sodium ion.
b. A capillary pore is many times larger in diameter than a glucose molecule.
c. The diameter of a red blood cell is many times greater than the diameter of a capillary pore.
d. A molecule of β globulin or γ globulin could just about squeeze through a capillary pore if it were lined up exactly
right.
e. All of the above are correct.
E
Suppose that the following conditions exist in a particular blood vessel: blood pressure (BP) inside vessel at inlet = 60 mm Hg, BP inside vessel at midpoint = 50 mm Hg, and BP inside vessel at outlet = 40 mm Hg. Pressure in the tissue fluid (interstitial fluid) immediately outside vessel = 5 mm Hg. Under these
conditions:
a. Perfusion pressure for blood flow through this vessel =20 mm Hg.
b. Perfusion pressure for blood flow through this vessel =15 mm Hg.
c. Distending pressure at the vessel midpoint = 55 mm Hg.
d. Distending pressure at the vessel midpoint = 45 mm Hg.
e. Both a and d are correct
E
Compared with the systemic circulation, the pulmonary circulation:
a. Carries more blood flow per minute.
b. Has a lower perfusion pressure.
c. Has a higher resistance to blood flow.
d. Carries blood that has a lower hematocrit.
e. Contains a higher blood volume.
B
Chapter 19 Electrical Activity of the Heart
Which of the following is true for both cardiac muscle and skeletal muscle?
a. The muscle forms a functional syncytium.
b. An action potential in the muscle cell membrane is required to initiate contraction.
c. Pacemaker cells spontaneously depolarize to threshold and initiate action potentials.
d. Frequent action potentials in motor neurons can cause a sustained (tetanic) muscle contraction.
e. Extracellular Ca2+ enters the muscle cell during an action potential and triggers the release of additional Ca2+ from the sarcoplasmic reticulum.
B
The normal pathway followed by a cardiac action potential is to begin in the SA node and then propagate:
a. Across the atria in the bundle of His.
b. Through the connective tissue layers that separate the atria and ventricles.
c. Across the atria and into the AV node.
d. From the left atrium to the right atrium.
e. From the left atrium to the left ventricle and from the right atrium to the right ventricle
C
At the moment when an action potential begins propagating slowly through the AV node in a normal resting dog, the
ventricular muscle cells are:
a. At their resting membrane potential.
b. Depolarizing slowly toward threshold for formation of an action potential.
c. Undergoing rapid depolarization at the beginning of an action potential.
d. At the plateau of an action potential.
e. Just ending their action potential (i.e., repolarizing back toward resting membrane potential).
A
During which phase of a normal ventricular action potential is it most likely that fast Na+channels are in an inactivated state, slow Ca2+ channels are open, and most K+ channels are closed?
a. Phase 0 (rapid depolarization)
b. Phase 1 (partial repolarization)
c. Phase 2 (plateau)
d. Phase 3 (repolarization)
e. Phase 4 (rest)
C
An increase in heart rate could result from:
a. An increase in sympathetic nerve activity to the heart.
b. A decrease in parasympathetic nerve activity to the heart.
c. An abnormally rapid decrease in permeability of SA node cells to K+ during diastole.
d. An abnormally rapid increase in permeability of SA node cells to Na+ during diastole.
e. All the above are correct
E
In which of the following arrhythmias will there be more atrial beats per minute than ventricular beats?
a. Complete (third-degree) AV block
b. Frequent premature ventricular contractions
c. Sick sinus syndrome (sinus bradycardia)
d. First-degree AV block
e. Ventricular tachycardia
A
Which of the following types of drugs would be the best choice to treat a patient with both supraventricular tachycardia and inadequate cardiac contractility?
a. Local anesthetic (fast Na+channel blocker)
b. Muscarinic cholinergic antagonist
c. Beta-adrenergic agonist
d. Cardiac glycoside (inhibits Na+, K+
pump)
e. Calcium channel blocker
D
Chapter 20 The Electrocardiogram
Which of the following intervals on an ECG most closely corresponds to the time required for propagation of a cardiac
action potential through the AV node?
a. RR interval
b. PR interval
c. ST interval
d. PP interval
e. QT interval
B
The T wave in a normal lead I ECG is:
a. Always negative.
b. Always positive if the R wave is positive.
c. Also known as the pacemaker potential.
d. Caused by the delay between atrial and ventricular depolarization.
e. Caused by ventricular repolarization.
E
What would the lead I ECG look like if an ectopic pacemaker in the free wall of the left atrium subsumed the role of the SA
node (i.e., “took over” the initiation of atrial action potentials)?
a. The ECG would appear normal.
b. The order of waves would be reversed (i.e. T-QRS-P, instead of P-QRS-T)
c. The P waves and T waves would appear normal, but there would be no R waves.
d. The P wave would be negative and the R wave would be positive.
e. The P wave would be negative and the R wave would be negative.
D
In which of the following arrhythmias will the ECG characteristically show the same number of P waves and QRS complexes?
a. Complete (third-degree) AV block
b. First-degree AV block
c. Ventricular tachycardia
d. Atrial flutter
e. All the above are correct.
B
Chapter 21 The Heart As a Pump
During a normal cardiac cycle, which of the following events happens soonest after the first heart sound is heard?
a. Atrial contraction begins.
b. The mitral valve opens.
c. Atrial depolarization begins.
d. Ventricular ejection begins.
e. The aortic valve closes
D
In the normal cardiac cycle:
a. The P wave in the electrocardiogram coincides with the beginning of ventricular ejection.
b. The second heart sound coincides with the beginning of isovolumetric relaxation.
c. Left ventricular pressure reaches its highest level just as the aortic valve closes.
d. Aortic pressure reaches its highest level at the beginning of ventricular systole.
e. The mitral valve is open throughout ventricular diastole.
B
An abnormality that causes a sustained decrease in left ventricular compliance is most likely to result in an increased:
a. Left ventricular stroke volume
b. Left atrial volume and pressure
c. Left ventricular afterload
d. Pulmonary blood flow
e. Left ventricular end-diastolic volume
B
Which of the following cause-and-effect statements is true for a normal heart?
a. Sympathetic activation causes end-systolic ventricular volume to increase.
b. An increase in ventricular preload causes end-diastolic ventricular volume to decrease.
c. Pacing the heart at a high rate causes stroke volume to decrease.
d. An increase in ventricular contractility causes systolic duration to increase.
e. An increase in ventricular contractility causes the external work of the heart to decrease
C
Chapter 22 The Systemic and Pulmonary Circulations
The magnitude of pulsations in blood pressure (caused by the pulsatile ejection of blood from the heart) is greatest in the:
a. Arteries
b. Arterioles
c. Capillaries
d. Veins
e. Venae cavae
A
Which of the following is a correct comparison between segments of the systemic circulation?
a. The aorta and large arteries have a higher resistance to blood flow than the capillaries.
b. The arterioles have a higher resistance to blood flow than the capillaries.
c. The veins have a higher resistance to blood flow than the capillaries.
d. The aorta and large arteries have a higher compliance than the veins.
e. The aorta and large arteries contain a greater volume of blood than the veins and venae cavae
B
If the heart suddenly stops beating in an otherwise normal dog, which of the following would be most likely to increase?
a. Mean circulatory filling pressure
b. Mean aortic pressure
c. Vena caval pressure
d. Perfusion pressure for the systemic circulation
e. Perfusion pressure for the pulmonary circulation
C