section 7

Question 1

parameters and conditions associated with microcytosis

Answer 1

Hgb produciton problem
less than 7 um

Question 2

parameters and conditions associated with macrocytosis

Answer 2

• dna synthesis problem
• greater than 7 um
• megaloblastic changes

Question 3

which rbc inclusions are viewed on supravital stain

Answer 3

heinz bodies and retics/baso stippiling

Question 4

cause of ovalo/ellipitocytes

Answer 4

hereditatry horizontal spectrin issue

Question 5

cause of target cells

Answer 5

increased membrane lipids causeing incrased SA and decreased hgb

Question 6

cause of sickle cells

Answer 6

abnormal hgbS in low oxygen environment forms stiff bundles

Question 7

cause of crystal cells

Answer 7

either issues with hgb c snails pr hgb sc birds

Question 8

cause of envelope cells

Answer 8

clear area on one side of condensed hgb from hgb c issues

Question 9

cause of burr cells

Answer 9

change in tonicity of intravascular fluid

Question 10

cause of acanthocytes

Answer 10

abnormal membrane lipids

Question 11

cause of shistocytes

Answer 11

inclusion removal leaves fragmented RBCs

Question 12

cause of tear cells

Answer 12

either from inclusion removal or extramedullary hematopoiesis

Question 13

cause of spherocytes

Answer 13

either from defect/loss of cell membran OR hereditary vertical spectrn issue

Question 14

cause of stomatocytes

Answer 14

hereditary failure of sodium potassium pumps increasing water in cell OR Rh deficiency

Question 15

cause of agglutination

Answer 15

due to rbc antibody causing cells to clump

Question 16

cause of rouleaux

Answer 16

increased Igs blocking zeta potential and lining cells up (removed with saline replacment)

Question 17

cause of howell-jolly bodies

Answer 17

remnant nuclease from busy BM

Question 18

cause of basophilic stippling

Answer 18

precipitated RNA in young RBCs (another form of retics)
course stippling from lead poisoning

Question 19

cause of pappenheimer bodies

Answer 19

granules of iron from ineffective utilization or excess
use of prussian blue stain to confirm

Question 20

cause of cabot rings

Answer 20

remnant nuclear membrane

Question 21

cause of heinz bodies

Answer 21

precipitated hgb from ox injury - failure of G6PD and hexose monophosphate pathway

Question 22

describe hgb H inclusions on supravital stain

Answer 22

looks like golf ball, evenly distributed dots (heinz are irregular)