section 5

Question 1

pelger huet anomaly

Answer 1

PMNs with less than 2 lobes

Question 2

hypersegmented PMNs

Answer 2

congenital/megaloblastic changes causing hypersegmentations of PMNs (greater than 6 nuclear lobes)

Question 3

barr bodies

Answer 3

drumstick protrusion in PMNs due to extra X chromosome (serve no function and do no harm)

Question 4

toxic granulation

Answer 4

• due to fewer mitotic divisions concentrating the primary granules in one cell
• seen with toxic vacuoles, dohle bodies and shift left
• increase in bacterial infections or toxicity

Question 5

toxic vacuolization

Answer 5

• due to a toxic environment or bacterial infection
• increased vacuoles in phagocytic cells
• seen with toxic gran, dohle bodies and shift left

Question 6

dohle bodies

Answer 6

• pale blue at the edge of the cell, remnant RNA
• due to increased tissue destruction and infections

Question 7

reactive lymphs

Answer 7

• activated T cells due to viral infection

Question 8

plasmacytoid lymphs

Answer 8

• activated B cells making antibody

Question 9

pyknotic cells

Answer 9

• degenerating cells with condensed nuclear material