Section 4 - Quiz Questions Flashcards

1
Q

Match the receptor with the drug whose action is mediated through it

Maropitant

A

Match the receptor with the drug whose action is mediated through it

Maropitant

Neurokinin-1 Receptor

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2
Q

**Match the receptor with the drug whose action is mediated through it **

Apomorphine

A

Match the receptor with the drug whose action is mediated through it

Apomorphine

Dopamine Receptor

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3
Q

Match the receptor with the drug whose action is mediated through it

Loperamide

A

Match the receptor with the drug whose action is mediated through it

Loperamide

Opioid Receptor

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4
Q

Match the receptor with the drug whose action is mediated through it

Ranitidine

A

Match the receptor with the drug whose action is mediated through it

Ranitidine

H2-Histamine Receptor

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5
Q

Match the receptor with the drug whose action is mediated through it

Erythromycin

A

Match the receptor with the drug whose action is mediated through it

Erythromycin

_Motilin Receptor _

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6
Q

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hyperkalemia

A

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hyperkalemia

Furosemide

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7
Q

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Glaucoma

A

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Glaucoma

Acetazolamide

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8
Q

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hyperaldertonism

A

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hyperaldertonism

Spironolactone

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9
Q

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hypokalemia in a patient with compromised hepatic function

A

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hypokalemia in a patient with compromised hepatic function

Triamtrene

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10
Q

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hypercalciuria (too much Ca2+ in urine)

A

Match each clinical problem listed with the diuretic drug most appropriate for treating it

Hypercalciuria (too much Ca2+ in urine)

Hydrochlorothiazide

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11
Q

**What pulmonary drug uses this mechanism of action? **

Relaxes bronchial smooth muscle by stimulating intracellular cyclic AMP production

A

What pulmonary drug uses this mechanism of action?

Relaxes bronchial smooth muscle by stimulating intracellular cyclic AMP production

_Clenbuterol _

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12
Q

What pulmonary drug uses this mechanism of action?

Relaxes bronchial smooth muscle by preventing breakdown of intracellular cyclic AMP

A

What pulmonary drug uses this mechanism of action?

Relaxes bronchial smooth muscle by preventing breakdown of intracellular cyclic AMP

Theophylline

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13
Q

What pulmonary drug uses this mechanism of action?

Decreases sensitivity of medullary cough center to sensory stimuli from airways

A

What pulmonary drug uses this mechanism of action?

Decreases sensitivity of medullary cough center to sensory stimuli from airways

Dextromethrophan

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14
Q

What pulmonary drug uses this mechanism of action?

Inhibits vagally-mediated broncho-constriction

A

What pulmonary drug uses this mechanism of action?

Inhibits vagally-mediated broncho-constriction

Glycopyrrolate

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15
Q

Which factor determines the minimum alveolar concentration for an inhalant anesthetic drug?

A

Which factor determines the minimum alveolar concentration for an inhalant anesthetic drug?

Solubility in lipids (oil:water partition coefficient)

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16
Q

Which enzymatic activity is inhibited by:

Omeprazole

A

Which enzymatic activity is inhibited by:

Omeprazole

H+, K+-ATPase

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17
Q

Which enzymatic activity is inhibited by:

Digoxin

A

Which enzymatic activity is inhibited by:

Digoxin

Na+, K+-ATPase

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18
Q

Which enzymatic activity is inhibited by:

Phosphodiesterase

A

Which enzymatic activity is inhibited by:

Phosphodiesterase

Pimobendan?

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19
Q

Which enzymatic activity is inhibited by:

Enalapril

A

Which enzymatic activity is inhibited by:

Enalapril

Angiotensin-converting enzyme

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20
Q

Which action of misoprostil (Cytotec) is required for effective ulcer healing?

A

Which action of misoprostil (Cytotec) is required for effective ulcer healing?

Gastric antisecretory action

21
Q

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure -

Decrease cardiac after-load by reducing arteriolar resistance

A

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure -

Decrease cardiac after-load by reducing arteriolar resistance

_Enalapril _

22
Q

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Decrease blood volume in order to reduce cardiac pre-load

A

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Decrease blood volume in order to reduce cardiac pre-load

Furosemide

23
Q

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Increase cardiac contracility

A

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Increase cardiac contracility

Digoxin

24
Q

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Reduce sympatho-adrenal influences on cardiac function

A

Which drug would best meet the following therapeutic goal of slowing the progression of congestive heart failure:

Reduce sympatho-adrenal influences on cardiac function

_Carvedilol _

25
Q

Match the mechanism of action with the most relevant GI drug:

Stimulates serotonin (5-HT) receptors

A

Match the mechanism of action with the most relevant GI drug:

Stimulates serotonin (5-HT) receptors

Cisapride

26
Q

Match the mechanism of action with the most relevant GI drug:

Stimulates motilin receptors

A

Match the mechanism of action with the most relevant GI drug:

Stimulates motilin receptors

Erythromycin

27
Q

Match the mechanism of action with the most relevant GI drug:

Stimulates opioid receptors

A

Match the mechanism of action with the most relevant GI drug:

Stimulates opioid receptors

Loperamide

28
Q

Match the mechanism of action with the most relevant GI drug:

Blocks substance P receptors

A

Match the mechanism of action with the most relevant GI drug:

Blocks substance P receptors

Maropitant

29
Q

Match the mechanism of action with the most relevant GI drug:

Blocks H2-Histamine receptors

A

Match the mechanism of action with the most relevant GI drug:

Blocks H2-Histamine receptors

Famotidine

30
Q

Which drug below has a mechanism of action that is most similar to that of theophylline?

A

Which drug below has a mechanism of action that is most similar to that of theophylline?

Pimobendan (blocks cAMP breakdown)

31
Q

Which bronchodilator drug raises intracellular cyclic AMP levels by increasing adenylate cyclase activity?

A

Which bronchodilator drug raises intracellular cyclic AMP levels by increasing adenylate cyclase activity?

Albuterol

32
Q

Which drug is most effective in promoting the healing of gastric ulcers in horses?

A

Which drug is most effective in promoting the healing of gastric ulcers in horses?

Omeprazole (Gastro-Gard)

33
Q

Which drug decreases the number of sodium channels expressed by renal tubular cells in a dog with hyperaldosteronism?

A

Which drug decreases the number of sodium channels expressed by renal tubular cells in a dog with hyperaldosteronism?

Spironolactone

34
Q

Which bronchodilating drug has excellent oral bioavailability, but a relatively narrow therapeutic index?

A

Which bronchodilating drug has excellent oral bioavailability, but a relatively narrow therapeutic index?

Theophylline

35
Q

Which drug is most effective in treating pulmonary edema in a patient with congestive heart failure?

A

Which drug is most effective in treating pulmonary edema in a patient with congestive heart failure?

Furosemide

36
Q

Which drug produces peripheral vasoconstriction but increases renal blood flow?

A

Which drug produces peripheral vasoconstriction but increases renal blood flow?

Dopamine

37
Q

Match the diuretic drug with its correct site of action in the nephron:

Acetazolamide

A

Match the diuretic drug with its correct site of action in the nephron:

Acetazolamide

Proximal Tubule

38
Q

Match the diuretic drug with its correct site of action in the nephron:

Furosemide

A

Match the diuretic drug with its correct site of action in the nephron:

Furosemide

_Loop of Henle, thick ascending limb _

39
Q

Match the diuretic drug with its correct site of action in the nephron:

Hydrochlorothiazide

A

Match the diuretic drug with its correct site of action in the nephron:

Hydrochlorothiazide

Early distal tubule

40
Q

Match the diuretic drug with its correct site of action in the nephron:

Spironolactone

A

Match the diuretic drug with its correct site of action in the nephron:

Spironolactone

_Late distale tubule/Collecting duct _

41
Q

Acute digitalis toxicity can produce:

(2)

A

Acute digitalis toxicity can produce:

  1. Ectopic pacemaker activity in the ventricles
  2. Gastrointestinal Disturbances
42
Q

Which pharmacotherapeutic regimen is reommended for early stage, class II congestive heart failure?

A

Which pharmacotherapeutic regimen is reommended for early stage, class II congestive heart failure?

A mild diuretic agent, like hydrochlorothiazide

43
Q

True/False

A dog in congestive heart failure that is given furosemide daily for a number of weeks will likely manifest an increased cardiac response to digitalis.

A

True/False

A dog in congestive heart failure that is given furosemide daily for a number of weeks will likely manifest an increased cardiac response to digitalis.

TRUE

44
Q

Which inhalant anesthetic agent has the lowest MAC value and induces anesthesia with the slowest onset?

A

Which inhalant anesthetic agent has the lowest MAC value and induces anesthesia with the slowest onset?

Methoxyflurane

45
Q

Which statement is correct regarding the mechanism by which mannitol acts as a diuretic?

A

Which statement is correct regarding the mechanism by which mannitol acts as a diuretic?

It acts as an osmotic stimulus to decrease water reabsorption from the nephron

46
Q

Which gastrointestinal drug acts as an AGONIST at CNS dopamine receptors?

A

Which gastrointestinal drug acts as an AGONIST at CNS dopamine receptors?

Apomorphine

47
Q

Which substance below is an example of an osmotic laxative?

Sorbitol

Mineral Oil

Bisacodyl

A

Which substance below is an example of an osmotic laxative?

Sorbitol

Mineral Oil

Bisacodyl

48
Q

Please indicate the main side effect associated with high efficacy natriuretic drug treatment

A

Please indicate the main side effect associated with high efficacy natriuretic drug treatment

Hypokalemic Metabolic Alkalosis

49
Q
A