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Pharmacology > Section 3 - Quiz Questions > Flashcards

Section 3 - Quiz Questions Flashcards

1
Q

**Match each drug with the appropiate receptor type that mediates the effects on which its medical use is based. **

Atenolol

Pilocarpine

Pancuronium

Prazosin

A

Match each drug with the appropiate receptor type that mediates the effects on which its medical use is based.

Atenolol - Beta Adrenergic Receptor

Pilocarpine - Muscarinic Cholinergic Receptor

Pancuronium - Nicotinic Cholinergic Receptor

Prazosin - Alpha Adrenergic Receptor

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2
Q

Choose the drug that produces these effects

Paralyzes skeletal muscle and inhibits respiration

A

Choose the drug that produces these effects

Paralyzes skeletal muscle and inhibits respiration

_Atracurium _

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3
Q

Choose the drug that produces these effects

Can produce dry mouth and pupillary dilation

A

Choose the drug that produces these effects

Can produce dry mouth and pupillary dilation

Atropine

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4
Q

Choose the drug that produces these effects

Increases heart rate and cardiac contractility

A

Choose the drug that produces these effects

Increases heart rate and cardiac contractility

Dobutamine

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5
Q

Choose the drug that produces these effects

Produces salivation, lacrimation, urination and defecation

A

Choose the drug that produces these effects

Produces salivation, lacrimation, urination and defecation

Neostigmine

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6
Q

Choose the drug that produces these effects

Decreases conduction in the atrio-ventricular node and inhibits ventricular tachyarrhthymias

A

Choose the drug that produces these effects

Decreases conduction in the atrio-ventricular node and inhibits ventricular tachyarrhthymias

Propanolol

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7
Q

Which drugs are effective in abolishing a supraventricular tachyarrhthmia that is due to impulse re-entry in the AV node?

(2)

A

Which drugs are effective in abolishing a supraventricular tachyarrhthmia that is due to impulse re-entry in the AV node?

  1. Propanolol (Class II AARD)
  2. Dilitizaem (Class IV AARD)
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8
Q

**Which class of anti-arrythmia drug lenthens the effective refractory period of centricular myocardial cells by slowing the retun of the ventricular action potential to the resting membrane potential? **

A

**Which class of anti-arrythmia drug lenthens the effective refractory period of centricular myocardial cells by slowing the retun of the ventricular action potential to the resting membrane potential? **

Class 3

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9
Q

**Which drugs act directly at the sino-atrial node to increase heart rate? **

(2)

A

**Which drugs act directly at the sino-atrial node to increase heart rate? **

  1. Atropine
  2. Isoproterenol
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10
Q

**Which type of cholinergic receptor mediates the effects of bethanechol in stimulating motility in the urinary bladder? **

A

**Which type of cholinergic receptor mediates the effects of bethanechol in stimulating motility in the urinary bladder? **

Muscarinic

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11
Q

This drug produces sedation by stimulating a2- adrenergic receptors in the central nervous system.

A

This drug produces sedation by stimulating a2- adrenergic receptors in the central nervous system.

Medetomidine

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12
Q

Which drug will relieve conduction block in the AV node?

A

Which drug will relieve conduction block in the AV node?

Atropine

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13
Q

**Which drug will decrease blood pressure if injected after administration of the antihypertensive agent phentolamine? **

A

**Which drug will decrease blood pressure if injected after administration of the antihypertensive agent phentolamine? **

Isoproterenol

(stimulates all beta adrenergic receptors)

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14
Q

Which cardiac receptor, when stimulated by an agonist, mediates a decrease in heart rate?

A

Which cardiac receptor, when stimulated by an agonist, mediates a decrease in heart rate?

M2-Muscarinic Cholinergic Receptor

(decrease pacemaker current in the SA node)

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15
Q

Which drug acts as a competitive antagonist at beta1-adrenergic receptors?

A

Which drug acts as a competitive antagonist at beta1-adrenergic receptors?

Atenolol

(is a “cardio-selective” beta1-AR antagonist)

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16
Q

What drug is used to correct urinary bladder atony (urinary retention)?

A

What drug is used to correct urinary bladder atony (urinary retention)?

Bethanechol

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17
Q

Which drug is used to correct Myasthenia gravis (poor cholinergic neuromuscular signaling)?

A

Which drug is used to correct Myasthenia gravis (poor cholinergic neuromuscular signaling)?

Neostigmine

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18
Q

Which drug is used to correct Bronchoconstrictive disease?

A

Which drug is used to correct Bronchoconstrictive disease?

Albuterol

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19
Q

Which drug is used to correct Supraventricular tachyarrhythmia (rapid AV conduction with impulse re-entry)?

A

Which drug is used to correct Supraventricular tachyarrhythmia (rapid AV conduction with impulse re-entry)?

Propanolol

20
Q

**The vasorelaxant effects of acetylcholine are mediated by the intracellular second messenger ______ produced in the vascular SMOOTH muscle cells. **

A

**The vasorelaxant effects of acetylcholine are mediated by the intracellular second messenger ______ produced in the vascular SMOOTH muscle cells. **

Cyclic GMP

21
Q

**Which anti-arrhythmic drug is less effective in patients with hypokalemia or alkalosis? **

A

**Which anti-arrhythmic drug is less effective in patients with hypokalemia or alkalosis? **

Lidocaine

22
Q

Which receptors are coupled through G proteins to decreased adenylate cyclase activity and reduced cyclic AMP production?

(3)

A

Which receptors are coupled through G proteins to decreased adenylate cyclase activity and reduced cyclic AMP production?

Alpha2-Adrenergic Receptors

M2 Muscarinic Cholinergic Receptors

M4 Muscarinic Cholinergic Receptors

23
Q

**The first muscles to be paralyzed in a dog that received an effective dose of pancuronium (skeletal muscle relaxant) are those involved with: **

A

**The first muscles to be paralyzed in a dog that received an effective dose of pancuronium (skeletal muscle relaxant) are those involved with: **

Tail wagging

24
Q

When applied directly to the eyes, which type(s) of drug can decrease intraocular pressure, an action that is useful in treating patients with glaucoma?

**(2) **

A

When applied directly to the eyes, which type(s) of drug can decrease intraocular pressure, an action that is useful in treating patients with glaucoma?

  1. Muscarinic Cholinergic Receptor Agonist
  2. Beta1-Adrenergic Receptor Antagonist
25
Q

Match the description with the drug that best fits

The skeletal muscle paralysis it produces can be reversed by neostigmine

A

Match the description with the drug that best fits

The skeletal muscle paralysis it produces can be reversed by neostigmine

Vecuronium

26
Q

Match the description with the drug that best fits

It increases renal blood flow by acting at D1-dopamine receptors

A

Match the description with the drug that best fits

It increases renal blood flow by acting at D1-dopamine receptors

_Fenoldopam _

27
Q

Match the description with the drug that best fits

It reverses the sedative and relaxant effects of xylazine (Rompun)

A

Match the description with the drug that best fits

It reverses the sedative and relaxant effects of xylazine (Rompun)

_Atipamezole _

28
Q

Match the description with the drug that best fits

It stimulates, then desensitizes neuromuscular-type nicotinic cholinergic receptors

A

Match the description with the drug that best fits

It stimulates, then desensitizes neuromuscular-type nicotinic cholinergic receptors

Succinylcholine

29
Q

Match the description with the drug that best fits

It inhibits both sympathetic and parasympathetic neurotransmission to peripheral organs.

A

Match the description with the drug that best fits

It inhibits both sympathetic and parasympathetic neurotransmission to peripheral organs.

Trimethaphan

30
Q

Match the description with the drug that best fits

It slows heart rate and atrioventricular conduction by a direct action on cardiac neurotransmitter receptors

A

Match the description with the drug that best fits

It slows heart rate and atrioventricular conduction by a direct action on cardiac neurotransmitter receptors

_Propanolol _

31
Q

Match the description with the drug that best fits

It stimulates all adrenergic receptors to increase cardiac output and systolic blood pressure, but decrease diastolic pressure

A

Match the description with the drug that best fits

It stimulates all adrenergic receptors to increase cardiac output and systolic blood pressure, but decrease diastolic pressure

Epinephrine

32
Q

Match the description with the drug that best fits

It increases skeletal muscle blood flow and stimulates glycogenolysis in the liver

A

Match the description with the drug that best fits

It increases skeletal muscle blood flow and stimulates glycogenolysis in the liver

_Clenbuterol _

33
Q

Which adverse effect of an acetylcholinesterase inhibitor is NOT prevented by the administration of atropine?

A

Which adverse effect of an acetylcholinesterase inhibitor is NOT prevented by the administration of atropine?

Skeletal Muscle Paralysis

34
Q

Which AARD most effectively slows phase 0 of the ventricular action potential, especially in partially depolarized myocardial cells?

A

Which AARD most effectively slows phase 0 of the ventricular action potential, especially in partially depolarized myocardial cells?

Lidocaine

35
Q

Which class of anti-arrhythmic drug lengthens the effective refractory period of ventricular myocardial cells by slowing the return of the ventricular action potential to the resting membrane potential?

A

Which class of anti-arrhythmic drug lengthens the effective refractory period of ventricular myocardial cells by slowing the return of the ventricular action potential to the resting membrane potential?

Class 3

36
Q

Which drug will produce a baroreceptor reflex-associated increase in heart rate?

A

Which drug will produce a baroreceptor reflex-associated increase in heart rate?

Phentolamine

37
Q

Which drug alleviates atrioventricular conduction block?

A

Which drug alleviates atrioventricular conduction block?

Atropine

38
Q

At therapeutic doses, which drug increases cardiac contractility, i.e. has a positive ionotropic effect?

A

At therapeutic doses, which drug increases cardiac contractility, i.e. has a positive ionotropic effect?

Dobutamine

39
Q

Which type of anticholinesterase drugs REVERSIBLY inhibits the catalytic activity of this enzyme by acting at the ESTERATIC site of acetylcholinesterase?

A

Which type of anticholinesterase drugs REVERSIBLY inhibits the catalytic activity of this enzyme by acting at the ESTERATIC site of acetylcholinesterase?

Carbamates (such as neostigmine)

40
Q

**Which drugs can dilate the pupil of the eye? **

(2)

A

Which drugs can dilate the pupil of the eye?

  1. Phenylephrine
  2. Atropine
41
Q

What are 2 drugs that will cause pupillary constriction?

A

What are 2 drugs that will cause pupillary constriction?

  1. Betaxolol
  2. Pilocarpine
42
Q

Molecular target for each AARD

Sotalol

A

Molecular target for each AARD

Sotalol

_Cardiac potassium channels _

43
Q

Molecular target for each AARD

Metoprolol

A

Molecular target for each AARD

Metoprolol

_Cardiac beta1-adrenergic receptors _

44
Q

Molecular target for each AARD

Lidocaine

A

Molecular target for each AARD

Lidocaine

_Cardiac sodium channels _

45
Q

Molecular target for each AARD

Diltiazem

A

Molecular target for each AARD

Diltiazem

_Cardiac calcium channels _

Pharmacology (7 decks)

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