secondmessengers etc Flashcards
give three examples of compounds that participate in signal transduction
insulin, glucagon, cytokines
what is it called when binding to the receptor cause two units to form a single structure
dimerization
how does the membrane allow dimerization to occur?
Its fluidity allows proteins to freely associate and dissociate, even in raft areas
MAP (kinase) stands for
mitogen activated protein
what does mitogen stimulate?
cell division
what is a second messenger?
a first messenger will bind to a receptor, causing a series of biochemical events which causes a change in concentration of a second messenger molecule within the cell, this then causes further reactions
MAP kinase uses a _ pathway
signal transduction
cGMP and cAMP are examples of
second messengers
the enzymes that synthesize cAMP from ATP are called
cyclases
the enzymes that convert cAMP back in to ATP are called
decyclases
inside the cell, there is a greater calcium concentration in _
the lumen of endoplasmic reticulum
with increased concentration in the cytoplasm, calcium ions bind to the protein _
calmodulin
