SDL Development of Eye & Ear Flashcards

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1
Q

how does the optic vesicle differ from the lens placode with respect to its development? which one is derived from an outpocketing of neuroectoderm?

A

optic vesicle induces overlying ectoderm to differentiate into the lens

lens placode induces the differentiation of the neural retina (outpocketing of ectoderm)

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2
Q

how is the embryonic intraretinal space formed? what happens to this space?

A

formed from continued growth of the optic vesicle

the intraretinal space disappears as the two layers oppose each other

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3
Q

how is the embryonic intraretinal space related to an injury-induced detached retina in an adult?

A

a retinal detachment is a re-opening of the intraretinal space - sxs: sudden floaters, flashing lights, black curtain

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4
Q

what is the choroid fissure? what travels through it?

A

choroid fissure is an invagination of optic vesicle; the hyaloid artery passes through it

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5
Q

what happens to the choroid fissure during development? persistence of the choroid fissure results in what developmental defect?

A

the choroid fissure eventually fuses; failure to close results in coloboma iridis

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6
Q

what is unique about the smooth muscles of the pupil as regards to their developmental origin?

A

the smooth muscles are unique in that they are derived from neuroectoderm of the optic cup

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7
Q

how does the sclera and choroid form? which is continuous with dura mater?

A

sclera formed from an outer layer of eye promordium surrounded by mesenchyme- continuous with dura mater/cornea

the choroid formed from inner vascular pigmented layer- continuous with pia and iris

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8
Q

the iridopupillary membrane is derived from which germ layer? what happens to this membrane?

A

mesoderm

later disappears

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9
Q

what defect occurs if the iridopupillary membrane persists in the adult?

A

there’s an iridopupillary membrane covering the pupil

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10
Q

what is coloboma iridis?

A

opening of pupil due to failure to close the choroid fissure

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11
Q

what is aniridia?

A

absence of the iris

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12
Q

what is aphakia?

A

absence of the lens

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13
Q

how do the otic vesicles form? what germ layer are they from?

A

invagination of the otic placodes forms the otic pits which then separate from the surface ectoderm*

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14
Q

which parts of the otic vesicle give rise to the semicircular canals? which parts give rise to the cochlear ducts?

A

dorsal component forms semicircular canals

ventral component forms cochlear duct

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15
Q

are semicircular canals/cochlear duct ectodermal, endodermal or mesodermal in origin?

A

ectodermal

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16
Q

what is the embryological origin of the organ of corti?

A

outer ridge/basement membrane of cochlear duct

17
Q

how do the middle ear ossicles develop?

A

develop in mesenchyme from pharyngeal arch cartilage; then mesenchyme disappears forming continuity with the tympanic cavity

18
Q

what is a result of the persistence of the transient meatal plug?

A

contribute to congenital deafness