SCT II - Resporation Nuclei Flashcards
Which central pattern generator (pacemaker) is responsible for inspiration?
Pre-Botzinger Complex (PBC)
Which central pattern generator (pacemaker) is responsible for expiration?
Retrotrapezoid Nucleis (RTN)
AKA
Parafacial Respiratory Group (PFRG)
During passive breathing, what inhibits and stimulates the PBC?
Inhibition: inflation of lungs, to avoid infinite inhalation
Stimulation: deflation of lungs, to start cycle again
What is the premotor neuron group(s) responsible for inspiration (passive/forced)?
Dorsal Respiratory Group (DRG): Passive
Rostral part of Ventral Respiratory Group (rVRG): Forced
Which muscle(s) is the DRG responsible for during forced breathing?
Diaphragm M. through Phrenic N.
Which muscle(s) is the rVRG responsible for during forced breathing?
All accessory muscles
Name the input(s) and output(s) for the DRG
Input: CN X, CN IX, Chemo- + Baroreceptors, Pontine circuit
Output: Phrenic N. + Pontine circuit
What are the premotor neuron group(s) responsible for expiration (passive/forced)?
Botzinger Complex (BotC): Passive
Caudal part of Ventral Respiratory Group (cVRG): Forced
What special function does the DRG have?
DRG activates BotC, which in turn inhibits DRG, allowing expiration to take place!
What is the pontine circuit responsible for inspiration?
Parabrachial Nucleus
AKA
Apneustic Area
What is the pontine circuit responsible for expiration?
Kolliker-Fuse Nucleus
AKA
Pneumotaxic Center
What inhibits the Parabrachial Nucleus (Apneustic Area)?
- Vagal input
- Kolliker-Fuse Nucleus (Pneumotaxic Center)
What’s the function of the Kolliker-Fuse Nucleus (Pneumotaxic Center)?
- Reduces duration of inspiration
- Increases ventilation rate by reducing duration of each breathe (more breaths)
What is normal-pattern breathing called?
Eupnea
What is breathing called with damage to the Kolliker-Fuse nucleus?
Apneusis
