Screening Flashcards

1
Q

Validity/accuracy

A

Ability of a screening to test measure the actual value

Actual value measured is using gold standard

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2
Q

Predictive value

A

Diagnostic power of a test

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3
Q

PPV NPV

A

Positive predictive value
Probability of having a disease after a positive test

Npv
“ not having disease after negative test

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4
Q

Diagnostic power of inclusion and exclusion

A

Inclusion- ppv

Exclusion- npv

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5
Q

Reliability/repeatability/precision

A

Test will give same values when repeated in the same person under the same condition

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6
Q

The different variations in reliability

A

Subject variation
Instrument variation
Observer variation

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7
Q

Kappa’s coefficient

A

To measure degree of interobserver agreement

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8
Q

Sensitivity And formula

A

Ability of the test to detect true positive
True positive divided by diseased positive

(Try to think what specificity is too :P)

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9
Q

Ideal property of a screening test

A

Sensitivity

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10
Q

PPV and prevalence relation

A

Directly proportional

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11
Q

Npv and prevalence relation

A

Inversely proportional

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12
Q

Ppv and fp relation

A

Inversely

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13
Q

Sensitivity and specificity relation

A

Inversely proportional

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14
Q

Which are the constant properties

A

Sensitivity and specificity
Inherent properties
Will not change with prevalence

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15
Q

Parallel test describe

A

3 tests done together
Any 1 test positive- disease +
All 3 tests negative-disease -

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16
Q

Sequential testing describe

A

2 tests done in sequence
1st test -ve - don’t repeat next test
1st test +ve -2nd test

17
Q

Know the relations of sensitivity/specificity/fp/fn/npv/fpv for parallel and sequential testing

A

You didn’t skip that did you -.-

18
Q

Likelihood ratio + -

A

LR+ sens/1-spec

LR- 1-sens/spec

19
Q

ROC curve

A

Receiver operating characteristic curve

To assess performance of a diagnostic test

20
Q

Area under curve in ROC

A

Performance,accuracy

21
Q

If disease fatality is more which parameter should be important

A

Increase sensitivity

22
Q

If treatment is costly and has more adverse effect which parameter should be involved

A

Increased specificity

23
Q

Lead time

A

Advantage gained by screening

Between point of detection and diagnosis

24
Q

Screening should be done between which points

A

B and C

If you’re super clueless pls check the notes

25
Q

How do we decide screening time

A

Based on critical point

26
Q

Prospective screening

A
Others are benefitted 
For communicable disease
Eg.hiv among prostitutes
Screening of immigrants 
COVID
TB
27
Q

Prescriptive screening

A
Own benefit 
NCDs
Eg.neonatal screening 
PAP smear 
Breast self examination