Sclerosing Lesions

Question 1

What is sclerosing lesions and what can it cause?

Answer 1

Sclerosing adenosis
Radial scar/complex sclerosing lesion
Benign disorderly proliferation of acini and stroma
Can cause mass or calcification

Question 2

What can sclerosing lesions mimic?

Answer 2

May mimic carcinoma

Question 3

Presentation of sclerosing adenosis?

Answer 3

Pain, tenderness or lumpiness/thickening
Asymptomatic
Age 20-70
Benign lesion with negligible risk of subsequent carcinoma

Question 4

How does radial scar present?

Answer 4

Wide age range

Common & incidiental

Question 5

What investigation diagnoses radial scar?

Answer 5

Mammography

Question 6

Pathology of radial scar present?

Answer 6

Stellate architecture
Central puckering
Radiating fibrosis

Question 7

Histology of radial scar?

Answer 7

Fibroelastic core
Radiating fibrosis containing distorted ductule
Fibrocystic change
Epithelial proliferation

Question 8

Treatment of radial scar?

Answer 8

Excise or sample extensively by vacuum biopsy