schizophrenia psurg Flashcards
4 phases in developing schizophrenia
Premorbid, prodromal, schizophrenia, residual phase
premorbid phase 1
social maladjustment, social withdrawal, irritibility, and antagonistic thoughts and behavior; shyness, family hx, mild s/s, functioning
prodromal phase 2
length 2-5 yrs; begins with a change from premorbid and extends until onset of frank pyschotic s/s; substantial functional impairment, sleep disturbance, anxiety, irritability, depressed mood, poor concentration, fatigue, deterioration in role function, social withdrawal; Positive s/s perceptual abnormaliites, ideas of reference, suspiciousness; herald onset of phase 3 schizophrenia; no school, no friends, no sleep
Schizophrenia phase 3
Active phase; +/- psychotic s/s prominent; consist of characteristic sypmtoms, social/occupational dysfunction, duration, schizoaffective and mood d/o; substance/GMC, relationship to a pervasive developmental d/o
Residual phase 4
(+) s/s of active phase absent; (-) s/s remain
Criteria for Schizophrenia: Characteristic s/s
lasting 1 mon, 2+ of s/s: delusions, hallucinations, disorganized speech (frequent derailment or incoherence), grossly disorganized or catatonic behavior, negative psychotic s/s (affective flattening, alogia/no words, or avolition/no drive)
criteria for Schizophrenia: social occupational dysfunction
work and self-care markedly below level before onset, or failure to achieve expected level of interpersonal, academic, or occupational achievement
criteria for schizophrenia: duration
continuous for at least 6 mon disturbance, with 1 mon of criteria 1
3 characteristics of psychosis
disorganization (thought and action not congruent), social functioning, lost contact with reality
Typical onset of pyschosis
teens and early 20s
with schizophrenia, rate of suicide is
higher
Predisposing factors
biological: genetic, neurotransmitter, anatomical and associated dz; Psychological: family (lack of love NOT a cause), stress (precipitate flare up but NOT a cause); Environmental: sociocultural
Major neurotransmitter in psychosis
Dopamine D2; then serotonin 5-HT
anatomical & associated dz are
flu virus during pregnancy, epilepsy, born with smaller frontal lobe for higher function
Transactional Model for schizophrenia
Start with precipitating event stressful/threatening to a weak ego; genetic influence; prenatal viral infx; abn brain structure and epilepsy/Huntington’s dz, brain tumor, Parkisonism, Inadequate Coping Skills; Primary Cognitive Appraisal: perceived threat to self; Secondary Cognitive Appraisal: weak ego, poor coping mechanism so initiate Defense Mechanism: denial, regression, projection, identification, religiosity; Response is Adaptive or Maladaptive; Maladaptive = psychotic episode and exacerbation of s/s (hallucination, delusions, social isolation, violence, inapporpriate affect, bizarre behavior, apathy, autism
Positive s/s of schizophrenia
content of thought: delusions, religiosity, paranoia, magical thinking; form of thought associative looseness, neologism, concreate thinking, clang associations, word salad, circumstantiality, tangentiality, mutism, perseveration; sense of self: echolalia, echopraxia, identification and imitation, depersonalization
Negative s/s of schizophrenia
Affect: inappropriate affect, bland or flat affect, apathy; Volition: inability to initiate goal-directed activity, emotional ambivalence; Impaired interpersonal functioning and relationship to the external world: autism, deteriorated appearance; Psychomotor Behavior: anergia, waxy flexibility, posturing, pacing and rocking; Associated features: anhedonia, regression
delusion
positive: fixed false belief (e.g. persecution from FBI, grandeur of I am Jesus, reference of I must break the code, control or influence of this dental filling controls what I think, somatic of the 70 yo pregnancy, nihilistic of I have no stomach)
religiosity
positive: praying all the time, affects functionality; culture appropriate
Paranoia
positive: my food has been poisoned
magical thinking
positive: it’s raining, the sky is sad.
erotomania
positive: Brad Pitt loves me.
associative looseness
positive: ideas kinda connect
neologism
positive: made up words; RN find the meaning
concreate thinking
positive: very literal; RN don’t use abstract thought
clang associations
positive: rhyme
word salad
positive: random words with no connection between words
circumstantiality
positive: so many details, can’t get to the point
tangentiality
positive: moves from subject to subject, no point
Mutism
positive: inability/refusal to speak
hallucinations
positive: false sensory perception; auditory hear voices, visual flashes of light, tactile crawling under skin, gustatory tastes of poop, olfactory smells like burning
Illusion
positive: misinterpret object; the real trash can is a dog illusion