Schizophrenia - MacIntyre Flashcards
psychosis
symptoms, not diagnosis
distorted perception of reality
delusion
fixed false belief
bizarre - not possible
non-bizarre - could be true
hallucinations
false sense perception - not with external stimulus
borderline personality disorder
only PD with hallucinations
schizophrenia
dementia praecox
split mind
epidemiology of schizophrenia
M = F
late teens early 20s
increased suicide risk
more likely victim of violence
prodromal period
of schizo
first break
diagnosis of schizophrenia
> 2 of following - for significant portion of 1 month
- delusions
- hallucinations
- disorganized speech
- grossly disorganized or catatonic behavior
- negative sx
social occupational dysfunction
for at least 6 months
positive symptoms
have something you don’t want
hallucinations and delusions
mainly auditory hallucinations
disorganized speech/behavior
negative symptoms
lack of motivation
affective blunting of emotion
cognitive blunting
impaired social fxn and social withdrawal
path of schizophrenia
cause unknown
increase genetic family risk
infection - toxoplasmosis gondii
marijuana - accelerate change toward schizo
ventricular enlargement - 3rd** and alteral
prefrontal cortex connections altered
NT of schizophrenia
dopamine
serotonin
glutamate
tx schizophrenia
antipsychotics first line
typicals and atypicals
akathisia
jump out of skin
4 As of schizophrenia
association - loose
autism - social behavior issues
ambivalent - no motivation
affect - flat
torticollis
MC dystonia side effect of antipsychotics
abnormal head/neck position
tardive dyskinesia
late onset
reduce suicidality
clozapine
agranulocytosis
clozapine
neuroleptic malignant syndrome
with antipsychotic use
can’t regulate temp, muscle rigidty and break down
kidney failure
fatal usually
outcome of schizophrenia
lower life expectancy
poor prognosis if untreated
schizophreniform disorder
schizophrenia - 1-6 months
majority progress
schizoaffective disorder
schizophrenia + mood disorder or bipolar
2 weeks schizophrenia - even when no mood changes
tx anti-psychotics, mood stabilizer, antidepressant
brief psychotic disorder
psychosis >1 day but
postpartum psychosis
keep mother and baby safe
onset hours to weeks after birth
delusional disorder
> 1 month of delusion - erotomatic, persecutory, grandiose, jealous, somatic
women > men
mid late life
tx - psychotherapy - poor response to antipsychotics
poor response to antipsychotics
delusional disorder
delusional transfer
in partner of individual with delusional disorder
folie a deux
tx - separation
