Schizophrenia - MacIntyre Flashcards

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1
Q

psychosis

A

symptoms, not diagnosis

distorted perception of reality

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2
Q

delusion

A

fixed false belief

bizarre - not possible
non-bizarre - could be true

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3
Q

hallucinations

A

false sense perception - not with external stimulus

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4
Q

borderline personality disorder

A

only PD with hallucinations

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5
Q

schizophrenia

A

dementia praecox

split mind

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6
Q

epidemiology of schizophrenia

A

M = F
late teens early 20s

increased suicide risk

more likely victim of violence

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7
Q

prodromal period

A

of schizo

first break

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8
Q

diagnosis of schizophrenia

A

> 2 of following - for significant portion of 1 month

  • delusions
  • hallucinations
  • disorganized speech
  • grossly disorganized or catatonic behavior
  • negative sx

social occupational dysfunction

for at least 6 months

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9
Q

positive symptoms

A

have something you don’t want

hallucinations and delusions

mainly auditory hallucinations

disorganized speech/behavior

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10
Q

negative symptoms

A

lack of motivation
affective blunting of emotion
cognitive blunting
impaired social fxn and social withdrawal

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11
Q

path of schizophrenia

A

cause unknown

increase genetic family risk

infection - toxoplasmosis gondii

marijuana - accelerate change toward schizo

ventricular enlargement - 3rd** and alteral

prefrontal cortex connections altered

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12
Q

NT of schizophrenia

A

dopamine
serotonin
glutamate

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13
Q

tx schizophrenia

A

antipsychotics first line

typicals and atypicals

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14
Q

akathisia

A

jump out of skin

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15
Q

4 As of schizophrenia

A

association - loose
autism - social behavior issues
ambivalent - no motivation
affect - flat

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16
Q

torticollis

A

MC dystonia side effect of antipsychotics

abnormal head/neck position

17
Q

tardive dyskinesia

A

late onset

18
Q

reduce suicidality

A

clozapine

19
Q

agranulocytosis

A

clozapine

20
Q

neuroleptic malignant syndrome

A

with antipsychotic use

can’t regulate temp, muscle rigidty and break down
kidney failure
fatal usually

21
Q

outcome of schizophrenia

A

lower life expectancy

poor prognosis if untreated

22
Q

schizophreniform disorder

A

schizophrenia - 1-6 months

majority progress

23
Q

schizoaffective disorder

A

schizophrenia + mood disorder or bipolar

2 weeks schizophrenia - even when no mood changes

tx anti-psychotics, mood stabilizer, antidepressant

24
Q

brief psychotic disorder

A

psychosis >1 day but

25
Q

postpartum psychosis

A

keep mother and baby safe

onset hours to weeks after birth

26
Q

delusional disorder

A

> 1 month of delusion - erotomatic, persecutory, grandiose, jealous, somatic

women > men

mid late life

tx - psychotherapy - poor response to antipsychotics

27
Q

poor response to antipsychotics

A

delusional disorder

28
Q

delusional transfer

A

in partner of individual with delusional disorder

folie a deux

tx - separation