Depressive Disorders - Weiss Flashcards
depressive disorders
15% total population
-25% women
50 billion cost annually in US
2/3 ppl with depression
don’t realize they have it
only 20% those diagnosed with depression
receive appropriate tx
7x more likely to be unemployed
depression
depression epidemiology
average age 40yo
women > men
no socioeconomic correlation
higher prevalence - no close relationship
etiology of depression
unknown
-biologic, genetic, psychosocial
bio - dysregulation of NEs, serotonin, DA possible
genetics of depression
1st degree relative - 2-10x more likely
will respond similar to same tx**
adrenal axis and depression
hypersecretion of cortisol
dysthymia
chronic low grade depression
respond better to pharmacotherapy
dysthymia vs. major depression?
major depression
major depressive disorder
depressed mood
anhedonia - lack of interest
> 2 weeks
4 symptoms
sx - SIGECAPS
sx of major depressive disorder
S - sleep I - interest defect G - guilt E - energy deficit C - concentration issues A - appetite disorder P - psychomotor retardation S - suicidal
general appearance depression
appearance bad hygiene eye contact bad poor posture psychomotor agitation/retardation
will respond - if keep on encouraging
depression mental status exam
speech perceptual disturbance thought content suicide thought orientation memory concentration attention judgement, insight, reliability
antidepressants OTC
no - can trigger mania
