Schizophrenia and other Psychotic Disorder Flashcards
defined by abnormalities in one or more of the ff: delusions
hallucinations
disorganized thinking
disorganized abnormal motor bheavior
negative symptoms
schizophrenia
usually begins before age 25, persists throughout life and affects eprsons of all social classes
schizophrenia
demence precoce
benedict morel
described deteriorated patients whose illness began in adolescence
benedict morel
dementia precox
emil kraepelin
change in cognition and early onset of disorder
dementia precox
long term deteriorating course and clinical symptoms of hallucinations and delusions
emil kraepelin
discovered schizophrenia
eugene bleuler
schism means
separation
4 primary syptoms of schizophrenia
4As
Association
Affect
Autism
Ambivalence
risk factors of schizophrenia
environmental
genetic
medical illness
substance abuse
suicide risk
50% concordance rate which is 4-5x higher than dizygotic twins or the rate of occurence in first degree relatives
monozygotic twins
dopamine hypothesis of schizophrenia
hyperdopaminergia
why is their a loss of brain volume in schizophrenics
reduced densiy of axons, dendrites, synapses
what happens to cerebral ventricles of schizophrenics
lateral and 3rd ventricular enlargment and decreased cortical volume