Schizophrenia Flashcards
What is schizophrenia?
Combination of delusional ideations, hallucinations, disorganized speech/thinking, and bizzare behaviors
DSM-V criteria for schizophrenia
1: 2 of the following– (delusions, hallucinations, disturbed speech, disturbed behavior/catatonic, negative symptoms) ONE must be: delusions, hallucinations, or disturbed speech
2: ongoing for at least 6 months and ACTIVE sx for 1 month
3: not attributed to another condition
brain structure abnormalities associated with schizophrenia
large brain ventricles
What neurotransmitter plays a part in schizophrenia?
excess dopamine
Overactivity of what pathway causes positive sx?
mesolimbic pathway
Dysfunction of what pathway causes negative and cognitive sx?
mesocortical pathway
3 phases of schizophrenia
Prodromal
Active
Residual
What happens in the prodromal phase of schizophrenia?
social withdrawal and isolation
inappropriate affect
poor communication patterns
neglect of personal grooming
What happens in the active phase of schizophrenia?
full blown sx
psychotic break: delusions, hallucinations….
high risk of suicide
usually hospitalized
What happens in the residual phase of schizophrenia?
sx are no longer prominent, but haven’t gone away
5 types of schizophrenia
Catatonic Paranoid Residual Disorganized Undifferentiated
Catatonic schizophrenia
will usually need help with all ADLs no speech slow motor movement (statue like) stupor excessive negativism inappropriate/bizarre posture waxy flexibility echolalia echopraxia don't respond to antipsychotics respond better to benzos like lorazepam
echolalia
involuntary parrot like repetition of words spoken by others
echoprazia
meaningless imitation of motions made by others
Paranoid schizophrenia
auditory hallucinations preoccupied with one or more delusion usually of persecutory nature appear hostile, angry, scared, nervous increased risk of violence respond well to antipsycotics
Disorganized schizophrenia
inappropriate or flat affect disorganized behavior disorganized speech (word salad) usually look unkept, dirty, and primitive severe cognitive impairment looseness of associations extreme social withdrawal
Residual schizophrenia
past hx of at least 1 episode of psychosis
eccentric behavior
absence of prominent positive sx
social withdrawal and inappropriate affect (neg sx)
Undifferentiated schizophrenia
usually a mix of all other types of schizophrenia disorganized behavior positive sx (delusions and hallucinations)
4 sx groups of schizophrenia
positive
negative
cognitive
affective
positive sx of schizophrenia
adding something that normally isn’t there
hallucinations
delusions
illusions
disorganized speech (associative looseness)
bizarre behavior
negative sx of schizophrenia
take away something (harder to tx) blunted affect alogia (povery of thought) avolition (loss of motivation) anhedonia anergia social withdrawal